Search for dissertations about: "Histone modifications"

Showing result 1 - 5 of 53 swedish dissertations containing the words Histone modifications.

  1. 1. Clinical management of pancreatic cancer aided by histone signatures

    University dissertation from Lund University, Faculty of Medicine

    Author : Monika Bauden; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; Histone modifications; Tumor size; Biomarkers; Tumor; LC MS MS; Nucleosomics; Histone H1.3;

    Abstract : .... READ MORE

  2. 2. Chromatin structure and histone modifications in gene regulation

    University dissertation from Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Author : Carolina Åstrand; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In the living cell, DNA is densely packed into a chromatin structure constituting nucleosomal arrays. One nucleosome core particle includes a disc shaped protein octamer consisting of pairs of histones H2A, H2B, H3 and H4. 146 bp of DNA is wrapped in almost two turns around this protein complex. READ MORE

  3. 3. Chromatin, histones, and epigenetic tags

    University dissertation from Institutionen för biomedicin och kirurgi

    Author : Elisavet Koutzamani; Linköpings universitet.; Linköpings universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chromatin; histones; histone variants; epigenetics; histone H4 methylation; linker histone phosphorylation; MEDICINE Morphology; cell biology; pathology Cell biology Medical cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Medicinsk cellbiologi;

    Abstract : The fundamental building blocks of chromatin are the nucleosomes. Each such unit is composed of about 200 bp of DNA, the well-conserved core histones (H2A, H2B, H3 and H4) and a linker histone (H1). READ MORE

  4. 4. Genome-wide patterns of histone modifications in fission yeast

    University dissertation from Stockholm : Karolinska Institutet

    Author : Indranil Sinha; Södertörns högskola.; Karolinska Institutet.; Karolinska Institutet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : DNA is wrapped almost two times around a group of proteins called histones to form a chromosomal structure known as the nucleosome. Both DNA and histones can be modified with different chemical tags by several enzymes to activate or suppress a particular gene or group of genes. Histones can be covalently modified at several places. READ MORE

  5. 5. Epigenetic Regulation of Gene Transcription in Hematopoietic Tumors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marina Tshuikina Wiklander; Uppsala universitet.; [2008]
    Keywords : Medical sciences; IRF family; ICSBP IRF8; epigenetics; ATRA; TNFα; histone modifications; methylation; transcription; MEDICIN OCH VÅRD;

    Abstract : Epigenetic modifications were shown to play an essential role in tumorigenesis. Epigenetic mechanisms can alter transcription in several ways, through DNA methylation and/or through histone modification. DNA methylation at the TSS (transcriptional start site) has been implicated in tumor development and gene silencing. READ MORE