Search for dissertations about: "Hiv serum"

Showing result 1 - 5 of 56 swedish dissertations containing the words Hiv serum.

  1. 1. Retroviral and related nucleic acid processing enzymes expression and detection : Applications on clinical studies of HIV and HERVs

    Author : Raymond Awad; Amnon Hizi; Uppsala universitet; []
    Keywords : Medical sciences; Reverse transcriptase; endogenous retrovirus; deoxycytidine kinase; HIV; HERVS; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medical Virology; medicinsk virologi;

    Abstract : Reverse transcriptase (RT), the expression and detection of the enzyme marking the family Retroviridae, has been studied. A new RT activity assay adapted to 96-well microtitre plates is described. It uses a non- radioactive bromodeoxyuridine triphosphate (BrdUTP) substrate in a solid phase format. The assay was highly sensitive. READ MORE

  2. 2. On cerebrospinal fluid markers of HIV-1 infection

    Author : Lars-Magnus Andersson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; cerebrospinal fluid; AIDS dementia complex; ganglioside GD3; Tau proteins; neopterin; HIV-1 RNA; blood-brain barrier; albumin ratio; cultivation;

    Abstract : HIV-1 infects the central nervous system early in the course of infection and neurological complications are common in HIV-1-infected individuals. Approximately 20% of individuals with acquired immunodeficiency syndrome (AIDS) not treated with antiretroviral therapy develop a subcortical dementia, AIDS dementia complex (ADC). READ MORE

  3. 3. Short modified peptides and their metabolites inhibit HIV replication

    Author : Elin Andersson; Göteborgs universitet; []
    Keywords : HIV-1; AIDS; GPG-NH2; G-NH2; antiretroviral drugs; Dipeptidyl peptidase IV; CD26; prodrug;

    Abstract : Several drugs inhibiting the replication of HIV-1, the causative agent of AIDS, are available today. However, HIV-1 treatment is hampered by side effects, poor adherence and development of resistance. READ MORE

  4. 4. Ligand-induced structural changes in HIV-1 envelope glycoprotein

    Author : Selina Poon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HIV-1;

    Abstract : The first step in HIV-1 entry is the interaction between viral envelope glycoprotein gp120 and CD4 receptor on permissive host cells. The interaction initiates a series of sequential conformational rearrangements that exposes epitopes involved in interaction with co-receptors. READ MORE

  5. 5. Invasive fungal disease in immunocompromised hosts with focus on diagnostics

    Author : Helena Hammarström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; invasive fungal disease; diagnosis; 1; 3-β-d-glucan; hematological malignancies; hematopoietic stem cell transplantation; HIV; lung transplant recipients; bronchiolitis obliterans syndrome;

    Abstract : Invasive fungal diseases (IFDs) are severe conditions affecting immunocompromised patients. The primary aim of this thesis was to explore different methods for diagnosis of IFD in different groups of immunocompromised patients. Papers I and II included patients with hematologic disorders. READ MORE