Search for dissertations about: "Human Adipocytes"

Showing result 1 - 5 of 112 swedish dissertations containing the words Human Adipocytes.

2. 1. Human Adipocytes : Proteomic Approaches

   Author : Åsa Jufvas; Peter Strålfors; Alexander Vener; Maria V Turkina; Hans Jörnvall; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Type 2 diabetes is characterized by increased levels of glucose in the blood originating from insulin resistance in insulin sensitive tissues and from reduced pancreatic insulin production. Around 400 million people in the world are diagnosed with type 2 diabetes and the correlation with obesity is strong. READ MORE

4. 2. Insulin signalling in human adipocytes : mechanisms of insulin resistance in type 2 diabetes

   Author : Anna Danielsson; Peter Strålfors; Fredrik Nyström; Lena Stensson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; type 2 diabetes; insulin; insulin resistance; insulin signalling; phosphorylation; insulin receptor substrate 1; feedback control; Medical cell biology; Medicinsk cellbiologi;

   Abstract : Prevalensen av fetma ökar drastiskt i stora delar av världen och utgör en stor riskfaktor för att utveckla insulinresistens och typ 2 diabetes. Fettväven kan bli mycket stor om för mycket energi tas upp av kroppen. READ MORE

5. 3. Insulin signaling dynamics in human adipocytes : Mathematical modeling reveals mechanisms of insulin resistance in type 2 diabetes

   Author : Elin Nyman; Peter Strålfors; Gunnar Cedersund; Pierre De Meyts; Linköpings universitet; []
   Keywords : ;

   Abstract : Type 2 diabetes is characterized by raised blood glucose levels caused by an insufficient insulin control of glucose homeostasis. This lack of control is expressed both through insufficient release of insulin by the pancreatic beta-cells, and through insulin resistance in the insulin-responding tissues. READ MORE

6. 4. Effects of immunosuppressive drugs on human adipose tissue metabolism

   Author : Maria J Pereira; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; tacrolimus; rapamycin; glucocorticoids; new onset diabetes after transplantation; adipocytes; insulin signalling; glucose uptake; lipolysis; lipogenesis;

   Abstract : The immunosuppressive agents (IAs) rapamycin, cyclosporin A and tacrolimus, as well as glucocorticoids are used to prevent rejection of transplanted organs and to treat autoimmune disorders. Despite their desired action on the immune system, these agents have serious long-term metabolic side-effects, including dyslipidemia and new onset diabetes mellitus after transplantation. READ MORE

7. 5. Glucose and glycerol transport in adipocytes from a structural perspective

   Author : Peng Huang; Medicinsk strukturbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; glucose and glycerol metabolism; glucose transporters; aquaglyceroporins; glucose transporter 4; aquaglyceroporin 7; protein and protein interaction; structure; single particle cryo-EM;

   Abstract : Adipocytes are crucial energy reservoirs to maintain metabolic homeostasis of glucose and lipids in the human body.Glucose transporters (GLUTs) and aquaporins (AQPs) play an important role in metabolic regulation of glucose andlipids in human adipocytes. READ MORE