Search for dissertations about: "Human endogenous retrovirus sequences"

Showing result 1 - 5 of 10 swedish dissertations containing the words Human endogenous retrovirus sequences.

2. 1. Human Endogenous Retroviruses: Studies on Transcriptional Activity and Genetic Variability

   Author : Patrik Medstrand; Malmö Klinisk virologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; virology; bacteriology; HERVs; Human endogenous retrovirus sequences; reverse transcriptase; Microbiology; differential RNA expression.; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Abstract : Endogenous retroviruses (ERVs) are believed to be remains of germ-line infections that have become fixed in the population. They are involved in pathophysiological conditions, in mechanisms leading to infection protection, and directly in the physiology of the organism by participating in the regulation of cellular gene expression. READ MORE

4. 2. Studies of human endogenous retroviruses and of the TGF-beta signaling pathway

   Author : Christian Kjellman; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; high-density filter array; gliom; TGF-beta; XA34; Human endogenous retrovirus; HERV-F; transplantation; serologi; Immunologi; serology; Immunology;

   Abstract : The human genome, in common with all mammalian genomes, carries a high load of inheritable retroviral sequences. We have identified and characterized a novel family of these endogenous retroviruses and have named this family HERV-F as based on the primer binding sites of three members. READ MORE

5. 3. Transcription, splicing and genetic structure within the human endogenous retroviral HERV-H family

   Author : Mats Lindeskog; Institutionen för naturgeografi och ekosystemvetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; immunosuppressive envelope protein; RNA splicing; Human endogenous retrovirus; transcription; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Abstract : Human endogenous retroviruses (HERVs) are remains of ancient retroviral infections of the germ line and constitute as much as 3 % of the human genome. HERVs are genetic elements that potentially may provide important biological functions by several different mechanisms. READ MORE

6. 4. Endogenous Retroviral RNA Expression in Humans

   Author : Lijuan Hu; Jonas Blomberg; Göran Friman; Francois Mallet; Uppsala universitet; []
   Keywords : Microbiology; Human endogenous retrovirus HERV ; HERVE; HERVW; betaretrovirus; gammaretrovirus; RNA expression; real time PCR; endometrium; endometriosis; brain tissue; reproductive tissue; ovarian cancer; ovary; neuroblastoma cell line; Mikrobiologi;

   Abstract : Human endogenous retroviruses (HERVs) constitute about 8% of the human genome. There are around 4000 pol-containing retroviral integrations in the human genome, which makes it impractical to measure each of them separately. READ MORE

7. 5. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors

   Author : Anders Bengtsson; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; Risk factors; Human parvovirus B19; Immune complex; Disease activity; Interferon-alpha; SLE; Retrovirus;

   Abstract : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). READ MORE