Search for dissertations about: "Human genome"

Showing result 1 - 5 of 292 swedish dissertations containing the words Human genome.

  1. 1. Genome and Transcriptome Comparisons between Human and Chimpanzee

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anna Wetterbom; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; chimpanzee; genome; transcriptome; comparative studies; exon arrays; next-generation sequencing; premature termination codon; alternative splicing; primate evolution; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Molecular medicine genetics and pathology ; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Molekylär medicin genetik och patologi ; Bioinformatik; Bioinformatics;

    Abstract : The chimpanzee is humankind’s closest living relative and the two species diverged ~6 million years ago. Comparative studies of the human and chimpanzee genomes and transcriptomes are of great interest to understand the molecular mechanisms of speciation and the development of species-specific traits. READ MORE

  2. 2. Human Adipocytes Proteomic Approaches

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Åsa Jufvas; Linköpings universitet.; Linköpings universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Type 2 diabetes is characterized by increased levels of glucose in the blood originating from insulin resistance in insulin sensitive tissues and from reduced pancreatic insulin production. Around 400 million people in the world are diagnosed with type 2 diabetes and the correlation with obesity is strong. READ MORE

  3. 3. Genome Variation in Human Populations Exploring the Effects of Demographic History and the Potential for Mapping of Complex Traits

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Åsa Johansson; Uppsala universitet.; [2006]
    Keywords : Genetics; genetics; evolution; microsatellie; SNP; selection; linkage disequilibrium; haplotype; Genetik;

    Abstract : A major challenge in human genetics is to understand the genetic variation underlying common diseases. In this thesis, I focus on forces creating differences between individuals and genomic regions, methods for characterizing genomic variation, and the association between genomic and phenotypic variation. READ MORE

  4. 4. Topics in Human Gene Mapping

    University dissertation from Mathematical Statistics, Centre for Mathematical Sciences, Lund University

    Author : Azra Kurbasic; Lunds universitet.; Lund University.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Statistik; actuarial mathematics; programming; Statistics; Mathematics; Naturvetenskap; Natural science; hidden Markov model; linkage analysis; Human genome; disease gene; programmering; aktuariematematik; operationsanalys; operations research; Matematik;

    Abstract : This thesis is interdisciplinary between Mathematical Statistics, Genetics, and Medicine. It mainly consists of topics in mathematical modelling of the correlation of inheritance of genes and disease in a family, a method called linkage analysis. It is organized as follows. READ MORE

  5. 5. Bioinformatic Analysis of Mutation and Selection in the Vertebrate Non-coding Genome

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mikael Brandström; Uppsala universitet.; [2007]
    Keywords : Biology; non-coding genome; selection; mutation; chicken; human; indel; microsatellite; sequence alignment; comparative genomics; bioinformatics; vertebrate; Biologi;

    Abstract : The majority of the vertebrate genome sequence is not coding for proteins. In recent years, the evolution of this noncoding fraction of the genome has gained interest. These studies have been greatly facilitated by the availability of full genome sequences. READ MORE