Search for dissertations about: "Human glandular kallikrein"

Found 4 swedish dissertations containing the words Human glandular kallikrein.

  1. 1. Human Glandular Kallikrein 2

    Author : Janita Lövgren; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; seminal plasma; semenogelin; PCI; serpin; zinc; cancer; prostate; PSA; hK2; serine protease; kallikrein; Clinical chemistry; Klinisk kemi;

    Abstract : Human glandular kallikrein 2 (hK2) is a serine protease, which is predominantly expressed by the prostate gland and found in seminal plasma at mean levels of 6 mg/ml. It has 79% amino acid sequence identity with prostate-specific antigen (PSA or hK3). READ MORE

  2. 2. Human glandular kallikrein 2 (hK2) in prostate cancer: Clinical and Methodological studies

    Author : Charlotte Becker; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; screening; prostate cancer; PSA; Human glandular kallikrein; hK2; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Human glandular kallikrein 2 (hK2) is a predominantly prostate produced protein with many similarities to prostate-specific antigen (PSA). Just like for PSA elevated levels of hK2 can be found in men with protate cancer. We created an assay where hK2 in serum could reliably and with negligible cross-reactivity with PSA, be measured down to 0. READ MORE

  3. 3. Structure, evolution and expression of glandular kallikrein genes

    Author : Yvonne Ceder; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ileum.; Clinical chemistry; Klinisk kemi; Tissue distribution; Androgen responsive element; Ortholog; Evolution; Prostate cancer; Glandular kallikreins; Prostate-specific antigen;

    Abstract : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. READ MORE

  4. 4. The Kallikrein-Related Peptidases hK2 and PSA with Emphasis on Genetic Variation, Secretion, and Sperm Motility

    Author : Charlotta Sävblom; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human glandular kallikrein 2; KLK3; hk2; prostate-specific antigen; PSA; sperm motility; seminal plasma; androgen receptor; SNP; CAG; KLK2;

    Abstract : Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are secreted by the prostate into seminal plasma and through leakage into blood. This leakage increases rapidly in prostate disease, and PSA is used worldwide as a marker of prostate cancer. READ MORE