Search for dissertations about: "IA-2 autoantibodies"

Showing result 1 - 5 of 10 swedish dissertations containing the words IA-2 autoantibodies.

  2. 1. Aspects of ZnT8 autoimmunity in childhood type 1 diabetes

    Author : Cecilia K Andersson; Pediatrisk endokrinologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Zinc transporter; ZnT8 autoantibodies; HLA; islet cell autoantibodies; GAD65 autoantibodies; IA-2 autoantibodies; insulin autoantibodies; glucose tolerance;

    Abstract : Type 1 diabetes is one of the most common chronic diseases in childhood and adolescence with an increasing incidence worldwide. It is an autoimmune disease with many autoimmune markers, where the zinc transporter 8 autoantibody (ZnT8A) is the most recent autoantibody discovered. READ MORE

  4. 2. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

    Author : Henrik Borg; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; secreting systems; Endocrinology; seropositive; seronegative; slowly-progressive; Type 2; Type 1; classification; IA-2A; IA-2; GADA; GAD; ICA; islet antibodies; C-peptide; beta cell function; diabetes mellitus; adult-onset; sekretion; diabetologi;

    Abstract : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. READ MORE

  5. 3. Autoantibodies as markers of beta-cell autoimmunity in children

    Author : Hanna Holmberg; Johnny Ludvigsson; Mona Landin-Olsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Autoantibodies; Beta-cell autoimmunity; Children; Breast-feeding; HLA haplotypes; Insulin gene; Paediatric medicine; Pediatrisk medicin;

    Abstract : Type 1 diabetes (T1D) is a chronic disease caused by destruction of the insulin producing beta-cells in the pancreas. The incidence of T1D has increased rapidly, especially in the Western world and among young children. READ MORE

  6. 4. Organ-specific autoantibodies in Addison's disease and autoimmune polyendocrine syndrome type I

    Author : Annika Söderbergh; Uppsala universitet; []
    Keywords : Medical sciences; Addison s disease; APS I; Down syndrome; AIRE; autoantibodies; autoantigens; autoimmunity; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Assessment of autoantibodies is a valuable tool in the diagnostic procedure of autoimmune diseases. The aim of this study was to investigate the prevalence of different autoantibodies and their associations with disease manifestations in patients with Addison's disease and autoimmune polyendocrine syndrome type I (APS I). READ MORE

  7. 5. Triggers of autoimmunity. Studies on gestational events

    Author : Sabina Lindehammer; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet autoantibodies; pregnancy; type 1 diabetes; celiac disease;

    Abstract : Objective The primary aim of this thesis was to test whether gestational exposure to environmental factors may induce islet autoimmunity. The second aim was to determine to what extent the exposure to viruses or other environmental factors is a risk factor for type 1 diabetes in the offspring. READ MORE