Search for dissertations about: "ICSBP IRF8"

Found 1 swedish dissertation containing the words ICSBP IRF8.

2. 1. Epigenetic Regulation of Gene Transcription in Hematopoietic Tumors

   Author : Marina Tshuikina Wiklander; Fredrik Öberg; Kenneth Nilsson; Ugo Testa; Uppsala universitet; []
   Keywords : Medical sciences; IRF family; ICSBP IRF8; epigenetics; ATRA; TNFα; histone modifications; methylation; transcription; MEDICIN OCH VÅRD;

   Abstract : Epigenetic modifications were shown to play an essential role in tumorigenesis. Epigenetic mechanisms can alter transcription in several ways, through DNA methylation and/or through histone modification. DNA methylation at the TSS (transcriptional start site) has been implicated in tumor development and gene silencing. READ MORE