Search for dissertations about: "IKK"
Found 5 swedish dissertations containing the word IKK.
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1. Regulation of NF-κB by Calmodulin
Abstract : Cells experience numerous external signals which they must respond to. Such signals arriving at the cell surface are transduced via various signal transduction pathways and often ultimately result in regulation of transcription. READ MORE
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2. Calmodulin mediated regulation of NF-kappaB in lymphocytes
Abstract : NF-κB transcription factors are regulators of a wide spectrum of genes involved in immune responses and inflammation as well as cellular proliferation and survival. Transcriptionally competent NF-κB dimers are retained in the cytoplasm of resting cells by binding to inhibitors of NF-κB (IκBs). READ MORE
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3. Regulation of activation of NF-κB by Calmodulin in T-lymphocytes
Abstract : Nuclear factor kappa B (NF-kB) is a widely expressed family of transcription factors that are involved in a diverse number of processes. These include inflammation or differentiation, survival or apoptosis, and proliferation or cell cycle arrest. READ MORE
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4. Development and Application of Triple Specific Proximity Ligation Assays (3PLA)
Abstract : After the completion of the human genome project the human genome was annotated with the surprisingly small amount of 24 000 (www.ensemble.com) genes. READ MORE
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5. The nuclear factor k[kappa]B signal transduction pathway : its role in atherogenesis and intimal hyperplasia
Abstract : Vascular inflammation is a hallmark of major cardiovascular diseases such as atherosclerosis, and also suggested as a critical component implicated in intimal hyperplasia. Given its central role in regulating expression of inflammatory genes, the nuclear factor kappaB (NF-kappaB) signal transduction pathway was postulated to play an important role in these pathological processes. READ MORE
