Search for dissertations about: "IL 10 genetics"

Showing result 1 - 5 of 13 swedish dissertations containing the words IL 10 genetics.

  2. 1. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE

    Author : Anna-Karin B. Lindqvist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Systemic lupus erythematosus; complex diseases; genetic susceptibility; linkage analysis; genome scan; candidate gene; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Abstract : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. READ MORE

  4. 2. Seminal Influence on the Oviduct : Mating and/or semen components induce gene expression changes in the pre-ovulatory functional sperm reservoir in poultry and pigs

    Author : Mohammad Atikuzzaman; Heriberto Rodriguez-Martinez; Dominic Wright; Karl-Eric Magnusson; Maria Jenmalm; Matthias Laska; Patrice Humblot; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Seminal plasma; proteome peptidome; oviduct; gene expression; chicken; pig;

    Abstract : Internal fertilization occurs in birds and eutherian mammals. Foetal development, however, is either extra- respectively intra-corpore (egg vs uterus). READ MORE

  5. 3. Genetic studies of diabetes in northern Sweden

    Author : Sofia Mayans; Dan Holmberg; Mats Eliasson; Outi Vaarala; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; families; genetic; association; SNP; linkage; TCF7L2; CTLA-4; Calpain-10; Medical genetics; Medicinsk genetik;

    Abstract : Diabetes mellitus represents a group of metabolic disorders caused by both environmental and genetic factors. The two most common forms of diabetes are type 2 diabetes (T2D) and type 1 diabetes (T1D). T2D is associated with obesity and the disease is caused by insulin resistance and pancreatic b-cell dysfunction. READ MORE

  6. 4. Innate and acquired immunity to commensal bacteria

    Author : Christina Hessle; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The innate immune system recognises molecular patterns shared by large groups of micro-organisms. Monocytes and macrophages respond to microbes by production of substances which act in concert to promote effective clearance of bacteria. READ MORE

  7. 5. Analysis of effector pathways in arthritis

    Author : Nandakumar Kutty Selva; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; Genetik; cytogenetics; Arthritis; mice; monoclonal antibody; collagen type II; Histology; histochemistry; cytochemistry; Histologi; tissue culture; cytokemi; histokemi; Genetics; vävnadskultur; serologi; cytogenetik; Immunology; serology;

    Abstract : Rheumatoid arthritis (RA) is a multifactorial, polygenic autoimmune disease. For effective treatment and control of RA, understanding of disease pathways and identification of genes involved are essential. Animal models are efficient tools to identify such pathogenic mechanisms and genes underlying the disease process. READ MORE