Search for dissertations about: "IL-1 alpha"

Showing result 1 - 5 of 36 swedish dissertations containing the words IL-1 alpha.

2. 1. On the role of HMGB1 and IL-1 in tissue barrier defense

   Author : Cecilia Zetterström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The specialized epithelial surfaces of the lymphoepithelial tissue in the airways and the seminiferous epithelium of the testis are sites of host-environmental interaction at the same time as they serve important physiological functions in gas exchange and reproduction. The host response of a broken epithelial barrier requires rapid mechanisms to control the microflora and to prevent invasion of pathogens. READ MORE

4. 2. The prognostic significance of uPA, uPAR an d the cytokine IL-1-alpha in urinary bladder cancer

   Author : Maria Seddighzadeh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Urinary bladder cancer; urokinase; urokinase receptor; interleukin-1;

   Abstract : Tumor invasion and metastasis are the major causes of cancer-related death. Proteases are important for the invasive and metastatic propensities of tumors. We have studied the mechanism underlying endogenous expression of the serine protease urokinase plasminogen activator (uPA) by human breast cancer cells. READ MORE

5. 3. Immunopathogenic mechanisms in inflammatory myopathies

   Author : Pernilla Englund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Myositis; capillaries; muscle fibers; IL-1 alpha; MHC; adhesion molecules;

   Abstract : The idiopathic inflammatory myopathies (IIMs) are characterized by symmetrical, proximal muscle weakness and by inflammatory infiltrates in muscle tissue. Based on different clinical as well as histopathological features the IlMs can be separated into polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM). READ MORE

6. 4. Tobacco smoking and periodontal disease : some clinical, microbiological and immunological aspects

   Author : Lennart Boström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : gingival crevicular fluid; IL-1[beta]; IL-1ra; Il-6; periodontal bone height; periodontal surgery; periodontopathogens; TNF-[alpha]; smoking;

   Abstract : The main aim of the thesis was to evaluate the influence of smoking on the inflammatory response in periodontal disease. The overall study population included 347 patients: 224 men and 123 women, aged between 31-86 years, with moderate to severe periodontal disease. READ MORE

7. 5. Molecular and functional studies of interleukin-1a in the rat testis

   Author : Taranum Sultana; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Interleukin-l alpha; spermatogenesis; Leydig cells; Sertoli cells; calpain I and II;

   Abstract : The aim of the present study was to gain a better insight into the role of interleukin-1 alpha (IL-1 alpha) in testicular physiology. In testis, IL-1alpha acts as a paracrine mediator involved in the regulation of testicular functions. READ MORE