Search for dissertations about: "INR"

Showing result 1 - 5 of 28 swedish dissertations containing the word INR.

  2. 1. Studies on warfarin treatment with emphasis on inter-individual variations and drug monitoring

    Author : Abdimajid Osman; Tomas Lindahl; Peter Söderkvist; Marja-Liisa Dahl; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Warfarin; VKORC1; Haplotype; Prothrombin time; INR; Clinical chemistry; Klinisk kemi;

    Abstract : Waran används sedan 60 år som blodförtunnande läkemedel för att förebygga eller förhindra progress av blodproppssjukdom. I Sverige behandlas årligen cirka 1 % av befolkningen med waran. I Östergötland uppskattas antal waranpatienter till cirka 3000. Waran hämmar enzymet VKORC1 som ansvarar för vitamin K omsättningen i kroppen. READ MORE

  4. 2. Anticoagulation treatment in patients with a mechanical heart valve

    Author : Bartosz Grzymala-Lubanski; Anders Själander; Peter J. Svensson; David Bergqvist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mechanical heart valve; anticoagulation; warfarin; Time in Therapeutic Range TTR ; INR variability;

    Abstract : BackgroundEvery year about 2,500 patients in Sweden undergo surgery for heart valve disease, primarily in the aortic valve.  In contrast to the mitral valve, which can be repaired in 70% of the cases, the aortic valve is normally replaced by a mechanical or biological prosthesis. READ MORE

  5. 3. Two worlds, one goal : A Clinician’s Perspective on Laboratory Analyses in Anticoagulant Treatment

    Author : Kerstin Arbring; Tomas Lindahl; Srinivas Uppugunduri; Margareta Holmström; Gerd Lärfars; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; Warfarin; DOAC; PT-INR; VKORC1;

    Abstract : Almost precisely a century ago, in the 1920s and 1930s, cattle bled to death in North America after being fed moldy hay containing sweet clover, the yellow Melilotus officinalis, and the white Melilotus albus. The toxic substance in the hay inhibiting blood coagulation was identified and named dicumarol. READ MORE

  6. 4. Averaged linear energy transfer and other beam quality descriptors inr elation to relative biological effectiveness

    Author : Fredrik Kalholm; Niels Bassler; Iuliana Toma-Dasu; Emanuele Scifoni; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; LET; RBE; LQ-model; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : In radiotherapy with protons, a constant relative biological effectiveness (RBE) of 1.1 is traditionally applied, i.e. protons are assumed to be 10\% more effective than photons in killing cells. READ MORE

  7. 5. Tools for Outcome-informed management of mental illness : Psychometric properties of instruments of the Swedish clinical multicenter Quality Star cohort

    Author : Bo Ivarsson; Torsten Norlander; Lars Jacobsson; Karlstads universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Consumer satisfaction; Quality of Life; Perceived distress; Severe mental illness; Schizophrenia; Social function; Global Assessment of Functioning; MANSA; Gender; Brukartillfredsställelse; Livskvalitet; Upplevda besvär; Allvaligt psykisk störning; Schizofreni; Social funktion; Global skattning av psykosocial funktion; MANSA; Gender; Psychology with an emphasis on medical psychology; Psykologi inr. medicinsk psykologi;

    Abstract : The purpose of this thesis was to investigate the psychometric properties of three global user subjective measures of the ”The Quality Star” clinical review model: Consumer Satisfaction Scale, Global Quality of Life scale, and Perceived Global Distress scale. The mental health implementation context of this review model emphasizes the client as an agent of change, taking part in shared decision making in an empowered role as collaborative partner to the professional clinicians. READ MORE