Search for dissertations about: "In-vitro simulations"

Showing result 1 - 5 of 57 swedish dissertations containing the words In-vitro simulations.

  2. 1. Creating cell microenvironments in vitro

    Author : Patric Wallin; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell migration; lipid bilayers; cell differentiation; liquid handling; surface functionalization; Microfluidics; chemotractant gradients; mammalian cell culture; cell microenvironments; in vitro screening assay;

    Abstract : Stem cells have a great potential to bring about advancements in fields like developmental biology, drug discovery, cancer biology and tissue engineering. In order to be able to use stem cells to their full potential, it is important to have control over their behavior. READ MORE

  4. 2. Assessment of human swallowing using in-vivo and in-vitro approaches

    Author : Muhammad Waqas; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; in-vitro manometery; In-vitro simulations; In-vivo analysis; microstructure analysis; extensional rheology; dysphagia; Ultrasound viscometry; Bolus Rheology;

    Abstract : Texture modification is the most vital strategy to manage dysphagia: a condition in which food and beverages are difficult to swallow. Typically thickeners in the form of starch or gums are added to the food to increase the viscosity and thereby reduce the speed of bolus flow. READ MORE

  5. 3. Exploring the role of rheology in bolus flow using an in-vitro approach

    Author : Muhammad Waqas; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; extensional rheology; ultrasound viscometery; Bolus rheology; in vivo analysis; in vitro manometry; In-vitro simulations; degluitition; microstructure analysis; thickened fluids; Dysphagia;

    Abstract : Swallowing disorders, termed ‘dysphagia’, are more common in the elderly but can also affect younger persons. Approximately, 8% of the world’s population suffers from dysphagia. A Texture Modified Diet (TMD), which increases bolus viscosity to adjust for the sluggish bolus handling mechanism, is the most common intervention. READ MORE

  6. 4. Enzymatic studies of alcohol dehydrogenase by a combination of in vitro and in silico methods

    Author : Mikko Hellgren; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Karolinska Institutet Department of Medical Biochemistry and Biophysics; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The family of alcohol dehydrogenases (ADHs) catalyzes conversions of alcohols, ketons and aldehydes. The early discovery and isolation of ADH (1937) was followed by numerous investigations. It was also the first dimeric enzyme for which the threedimensional structure was determined (1974). READ MORE

  7. 5. Optical Analysis of biological media - continuous wave diffuse spectroscopy

    Author : Jan Sørensen Dam; Atomfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; spatially resolved diffuse reflectance; in vitro diffuse spectroscopy; continuous wave techniques; Nuclear physics; multivariate data analysis.; Kärnfysik; Fysik; Physics; Medicin människa och djur ; Medicine human and vertebrates ; Monte Carlo simulations; light propagation models; multiple scattering; Tissue optics; tissue optical properties; Fysicumarkivet A:2000:Sörensen Dam;

    Abstract : The main topic of this thesis is real-time quantification of relevant chromophores and light scattering elements in biological media. The presented methods and instrumentation are based on continuous wave (steady-state) optical measurements of (a) spatially-resolved diffuse reflectance from bulk media and (b) combined spatially-resolved and goniometric measurements of re-emitted light from thin samples. READ MORE