Search for dissertations about: "Ingela Lanekoff"
Showing result 1 - 5 of 6 swedish dissertations containing the words Ingela Lanekoff.
-
1. Analysis of phospholipids in cellular membranes with LC and imaging mass spectrometry
Abstract : Imaging mass spectrometry enables the creation of molecule specific images from the surface of a solid sample in vacuum. To solve the issue of bringing single cells into vacuum without altering their native distribution of molecules, a freeze fracture device that fits the time of flight secondary ion mass spectrometry (TOF-SIMS) IV instrument has been developed. READ MORE
-
2. Applications of nanospray desorption electrospray ionization mass spectrome : Analysis of lipids and metabolites in brain tissue sections and single cells
Abstract : .... READ MORE
-
3. Applications of nanospray desorption electrospray ionization mass spectrometry : In situ lipid and metabolite analysis from cells to tissue
Abstract : Ambient mass spectrometry (MS) has proved to be an important addition to the bioanalytical toolbox. These methods perform analyte sampling and ionization under atmospheric pressure, and require very little sample preparation other than the sampling process in front of the machine. READ MORE
-
4. Novel strategies to increase throughput and differentiate lipid isomers in mass spectrometry imaging : Development of computational tools and complex mass spectrometric methods for nanospray desorption electrospray ionization
Abstract : In this thesis, method development for improved analyte identification and throughput in mass spectrometry imaging (MSI) is discussed. In MSI, the spatial distribution of analytes from a sample is determined and visualized, information about the detected molecules interaction within the sample can thereby the deduced. READ MORE
-
5. Molecular Imaging of Diabetic Kidney Tissue and Binding Studies of Proinsulin C-peptide
Abstract : Diabetic kidney disease is a serious complication of diabetes with a complex and incompletely understood pathology. In this work, the molecular changes in diabetic rat kidneys at a very early disease stage were studied using nanospray desorption electrospray ionisation mass spectrometry imaging. READ MORE