Search for dissertations about: "Ingrid Øra"

Found 3 swedish dissertations containing the words Ingrid Øra.

  1. 1. Approaches to Treatment of Children with Advanced Neuroblastoma

    University dissertation from Ingrid Øra, Div. of Pediatric Oncology and Hematology, University Hospital Lund, 221 85 Lund, Sweden

    Author : Ingrid Øra; Lunds universitet.; Lund University.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; drug resistance; Pediatrics; hypoxia; apoptosis; arsenic trioxide; treatment; diagnosis; neuroblastoma; sympathetic nervous system; Pediatri; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Children with advanced neuroblastoma are at high risk for relapse of multidrug resistant disease, despite initial response to intensive multimodality treatment. Neuroblastomas have similarities with immature neuroblasts seen during embryonic development of the sympathetic nervous system (the origin of these tumors). READ MORE

  2. 2. Effects of arsenic trioxide and hypoxia in multidrug-resistant neuroblastoma

    University dissertation from Lund University, Faculty of Medicine

    Author : Jenny Karlsson; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical biology; Klinisk biologi; neuroblastoma; multidrug resistance; hypoxia; glucose-deficiency; cell death; Bax; Apoptosis; arsenic trioxide;

    Abstract : Neuroblastoma is a childhood tumour derived from the sympathetic nervous system. Although most children with neuroblastoma initially respond to treatment, approximately 50% of these patients relapse with multidrug-resistant tumours. Arsenic trioxide (As2O3) has been used for centuries to treat different clinical disorders including malignancies. READ MORE

  3. 3. Transcriptional regulation in neuroblastoma cells under normoxic and hypoxic conditions

    University dissertation from Annika Jögi, Västerg. 40, 211 21 Malmö

    Author : Annika Jögi; Lunds universitet.; Lund University.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytologi; onkologi; cancer; Cytology; HIF-2; HIF-1; hypoxia; Id; HES-1; bHLH; Neuroblastoma; neuronal differentiation;

    Abstract : The childhood malignancy neuroblastoma develops from early cells of the sympathetic nervous system (SNS), and the tumors often produce catecholamines. Neuroblastoma cells retain several characteristics of immature sympathetic cells including the expression of a number of transcription factors normally expressed during embryogenesis. READ MORE