Search for dissertations about: "Ingvarsson"

Showing result 1 - 5 of 21 swedish dissertations containing the word Ingvarsson.

  1. 1. Echocardiographic assessment of ventricular size and function in heart transplant patients

    Author : Annika Ingvarsson; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart Transplantation; Echocardiography; Speckle tracking; Left ventricular assist device;

    Abstract : AbstractThe overall aims of this thesis were to use echocardiography to non-invasively, delineate early structural andfunctional changes following orthotopic heart transplantation (OHT), and to define reference values in the contextof gender and bridging with mechanical circulatory support.Several factors might affect myocardial function in OHT patients rendering the use of normal values fortransthoracic echocardiography derived from healthy subjects unsatisfactory. READ MORE

  2. 2. Design of recombinant antibody microarrays for global proteome analysis

    Author : Johan Ingvarsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioteknik; oncoproteomics; Recombinant antibody microarray; scFv; Biotechnology; plasma proteome analysis;

    Abstract : Antibody-based microarrays are among the new, rapidly emerging technologies within the field of proteomics that has the potential to evolve into a key proteomic research tool, providing novel means to perform early diagnostics, identify biomarkers and gain insights into disease biology. The aim of this thesis, based on five original papers, was to develop antibody microarrays based on human recombinant scFv antibody fragments for large-scale comprehensive proteome analysis. READ MORE

  3. 3. Signalling mechanisms in B cell differentiation: Studies on specific human immune response in vitro

    Author : Sigurdur Ingvarsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Bioteknik; Biotechnology; CD44; CD40; Specific antibody secretion; B cells; Germinal centres; serology; transplantation; Immunologi; serologi;

    Abstract : We need to understand the major signalling events in human B cell differentiation in order to be able to regulate the generation of human antigen specific antibodies. This study has focused on the signalling mechanisms involved in generation of germinal centre reaction and secretion of specific antibodies by human B cells, using different in vitro immunisation technologies. READ MORE

  4. 4. Tipping the scale of resources : de-implementation of low-value care from an operant perspective

    Author : Sara Ingvarsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: The overarching goal within the field of implementation science is to generate knowledge that can contribute to bridging the gap between research and practice. Most studies focus on how to implement research findings, with the aim of using evidence-based interventions. READ MORE

  5. 5. Prevalence and Inheritance of Hip Osteoarthritis in Iceland

    Author : Thorvaldur Ingvarsson; Lund Ortopedi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; gene; inheritance; age standardiation; prevalence; THR; Hip; OA; traumatologi; Kirurgi; ortopedi; traumatology; orthopaedics;

    Abstract : Hereditary factors are suggested to contribute to osteoarthritis (OA), but their relative importance is uncertain. Moreover, the underlying specific variations at the genome level remain unknown. The prevalence of hip OA in Iceland was assessed by examining colon radiographs and was found to be at least 5-fold higher compared to Sweden and Denmark. READ MORE