Search for dissertations about: "Insulin Sensitivity"
Showing result 1 - 5 of 304 swedish dissertations containing the words Insulin Sensitivity.
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1. Insulin signalling in human adipocytes : mechanisms of insulin resistance in type 2 diabetes
Abstract : Prevalensen av fetma ökar drastiskt i stora delar av världen och utgör en stor riskfaktor för att utveckla insulinresistens och typ 2 diabetes. Fettväven kan bli mycket stor om för mycket energi tas upp av kroppen. READ MORE
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2. Fat cell insulin resistance : an experimental study focusing on molecular mechanisms in type 2 diabetes
Abstract : The aim of the present thesis was to further increase our understanding of mechanisms contributing to and maintaining cellular insulin resistance in type 2 diabetes (T2D). For this reason, the effects of high glucose and insulin levels on glucose transport capacity and insulin signaling, with emphasis on insulin receptor substrate 1 (IRS-1) were assessed in fat cells. READ MORE
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3. Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity
Abstract : Type 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. READ MORE
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4. Insulin Polymorphism Crystallographic Characterization of Insulin Microcrystals
Abstract : Insulin is a protein needed for the uptake of glucose from the circulating blood. In absence of sufficiently high insulin levels in the body or when the cells have a reduced sensitivity for insulin a disease state referred to as diabetes occurs. Treatment of diabetes generally requires daily injections of exogenous insulin. READ MORE
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5. Body Composition in Adolescents with Type 1 Diabetes : Aspects of Glycaemic Control and Insulin Sensitivity
Abstract : Excessive weight gain has frequently been reported in adolescents with type 1 diabetes, especially in girls. In general, puberty is associated with reduced insulin sensitivity that is further diminished by overweight. The causes and consequences of excessive weight gain in adolescents with type 1 diabetes are not fully understood. READ MORE