Search for dissertations about: "Interleukin-2 blood"

Showing result 1 - 5 of 21 swedish dissertations containing the words Interleukin-2 blood.

2. 1. Influence of FK506 on certain aspects of lymphocyte activation and lymphocyte-endothelial cell interactions in vitro

   Author : Håkan Karlsson; Avdelningen för medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytokine; adhesion molecule; endothelium; lymphocyte metabolism; interleukin 2 receptor; FK506; cyclosporin A; Mikrobiologi; bakteriologi; virologi; mykologi; Immunology; transplantation; serology; Microbiology; bacteriology; mycology; virology; Immunologi; serologi;

   Abstract : In the present thesis, the influence of the immunosuppressive drug FK506 on mitogen-induced changes in the expression of subunits a and ß of the IL-2 receptor by isolated human peripheral blood mononuclear cells has been studied. Up-regulation and release of the a-chain were potently depressed by FK506, even in the presence of exogenous IL-2. READ MORE

4. 2. Coagulation, fibrinolysis and inflammation in open surgery for infrarenal abdominal aortic aneurysm

   Author : Anders Holmberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Abdominal aortic aneurysm; blood coagulation; fibrinolysis; cytokines; leucocytes; flow cytometry; chemotaxis; lactoferrin; myeloperoxidase; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Abstract : Elective repair of infrarenal abdominal aortic aneurysm (AAA) carries a mortality of 4-8% and there is a substantial incidence of serious non-lethal complications. During surgery there is a situation of relative ischaemia and subsequent reperfusion of the lower part of the body. READ MORE

5. 3. Aspects on the cytokine load in trauma with special reference to blood components and local versus systemic cytokine activity

   Author : Marianne Kristiansson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Autotransfusion Coagulation Cytokines Cytokine inhibitors Fibrinolysis Infection Red blood cell concentrates Surgery Trauma. Stockholm 1997;

   Abstract : Cytokines and their inhibitors are thought to be involved in many of the pathophysiological changes associated with trauma and infection. Therapeutic measures such as transfusion of blood components could have a bearing on the systemic cytokine load in these conditions. READ MORE

6. 4. Genetic modification of human natural killer cells and possible applications thereof

   Author : Kyriakos Konstantinidis; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Natural killer cells; retroviral transduction; interleukin-2; endoplasmic reticulum targeting; green fluorescent protein; multiple myeloma;

   Abstract : Natural killer (NK) cells are dependent on the presence of interleukin-2 (IL-2) for their survival and for their cytotoxicity against tumor cells. Currently, for in vitro expansion of NK cells from peripheral blood mononuclear cells (PBMCs), IL-2 is of great importance. READ MORE

7. 5. Glucocorticosteroid effects on cytokine production: studies in a glucocorticosteroid resistance model and in allergic airway disease

   Author : Susanne Larsson; allergologi och palliativ medicin Lungmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GM-CSF; cytokine; glucocorticoids; budesonide; IL-2; IL-4; IL-12; asthma; allergic rhinitis; allergic airway inflammation; Respiratory system; Andningsorganen;

   Abstract : Glucocorticosteroids (GCS) are potent anti-inflammatory drugs, probably due to inhibitory effects on cytokine production. However, a small number of asthma patients seem GCS-resistant. Pro-inflammatory cytokines, such as interleukin-2(IL-2) and IL-4, produced during allergic airway inflammation have been proposed to induce the resistance to GCS. READ MORE