Search for dissertations about: "Ion channels"
Showing result 1 - 5 of 211 swedish dissertations containing the words Ion channels.
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1. Ion Tracks for Micro- and Nanofabrication : From Single Channels to Superhydrophobic Surfaces
Abstract : A method is described for preset-count irradiations between 1 and 100 ions singling-out individual ions from an ion beam with more than a billion ions arriving per second. The ion tracks are etched in a conductometric system with real-time evaluation of the acquired data. The etch process can be interrupted when reaching a preset channel diameter. READ MORE
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2. Modeling of voltage-gated ion channels
Abstract : The recent determination of several crystal structures of voltage-gated ion channels has catalyzed computational efforts of studying these remarkable molecular machines that are able to conduct ions across biological membranes at extremely high rates without compromising the ion selectivity. Starting from the open crystal structures, we have studied the gating mechanism of these channels by molecular modeling techniques. READ MORE
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3. Structural transitions of proton-gated ion channels : Involving pH sensing, heterogeneity and lipid interactions
Abstract : Studying protein structure and function involves analyzing the relationship between a protein's three-dimensional assembly and its dynamic biochemical activity. The superfamily of pentameric ligand-gated ion channels (pLGICs) constitutes a classic yet illuminating experimental system for structure-function studies. READ MORE
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4. Dendritic and axonal ion channels supporting neuronal integration : From pyramidal neurons to peripheral nociceptors
Abstract : The nervous system, including the brain, is a complex network with billions of complex neurons. Ion channels mediate the electrical signals that neurons use to integrate input and produce appropriate output, and could thus be thought of as key instruments in the neuronal orchestra. READ MORE
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5. Combining low resolution, high resolution, functional, and simulation techniques : In the study of pentameric ligand-gated ion channels
Abstract : Combining methods yielding different information is a powerful approach for understanding structural biology in general, and in particular systems such as pentameric ligand-gated ion channels (pLGICs). Pentameric ligand-gated ion channels are membrane proteins that sense chemical signals, which they convert to changes in membrane potential. READ MORE