Search for dissertations about: "José Sánchez"

Showing result 1 - 5 of 7 swedish dissertations containing the words José Sánchez.

  2. 1. Comparative network analysis of human cancer: sparse graphical models with modular constraints and sample size correction

    Author : José Sánchez; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Inverse covariance matrix; precision matrix; graphical models; high-dimension; low-sample; networks; sparsity; fused lasso; elastic net; cancer.; fused lasso;

    Abstract : In the study of transcriptional data for different groups (e.g. cancer types) it's reasonable to assume that some dependencies between genes on a transcriptional or genetic variants level are common across groups. Also, that this property is preserved locally, thus defining a modular structure in the model networks. READ MORE

  4. 2. Network models with applications to genomic data: generalization, validation and uncertainty assessment

    Author : José Sánchez; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Inverse covariance matrix; precision matrix; graphical models; high-dimension; low-sample; networks; sparsity; fused lasso; elastic net; cancer; TCGA pan cancer analysis; online resource; discriminant analysis; classification; networks;

    Abstract : The aim of this thesis is to provide a framework for the estimation and analysis of transcription networks in human cancer. The methods we develop are applied to data collected by The Cancer Genome Atlas (TCGA) and supporting simulations are based on derived models in order to reflect real data structure. READ MORE

  5. 3. Computing abundance constraints in Saccharomyces cerevisiae’s metabolism

    Author : Benjamín José Sánchez; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genome-scale modeling; lipidomics; proteomics; flux balance analysis;

    Abstract : The unicellular eukaryotic organism Saccharomyces cerevisiae (budding yeast) is routinely used for production of high-value chemical compounds in the biotechnology industry. To improve production yields, it is fundamental to understand cellular metabolism, i.e. all biochemical reactions that occur inside the cell. READ MORE

  6. 4. Energy Management in Smart Cities

    Author : Christian Francisco Calvillo Munoz; Lennart Söder; Alvaro Sanchez; José Villar; Rafael Cossent; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Energy system model; Smart city; Distributed energy resources; Distributed generation; EV; Metro; Energy markets; Planning and operation model; Energy Technology; Energiteknik;

    Abstract : Models and simulators have been widely used in urban contexts for many decades. The drawback of most current models is that they are normally designed for specific objectives, so the elements considered are limited and they do not take into account the potential synergies between related systems. READ MORE

  7. 5. Designing a Modern Skeleton Programming Framework for Parallel and Heterogeneous Systems

    Author : August Ernstsson; Christoph Kessler; José Daniel García Sánchez; Herbert Kuchen; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; High‐level parallel programming; Algorithmic skeletons; Heterogeneous systems; High‐performance computing;

    Abstract : Today's society is increasingly software-driven and dependent on powerful computer technology. Therefore it is important that advancements in the low-level processor hardware are made available for exploitation by a growing number of programmers of differing skill level. READ MORE