Search for dissertations about: "Karin Ridderstråle"

Found 1 swedish dissertation containing the words Karin Ridderstråle.

2. 1. Myc oncoprotein cofactor interactions : function, regulation and targeting

   Author : Karin Ridderstråle; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The members of the Myc-family of proto-oncoproteins c-Myc, N-Myc and L-Myc are transcription factors exerting their effect via protein-protein interactions. The Myc proteins are basic-helix-loop-helix-leucine-zipper (bHLHzip) transcription factors, which after heterodimerization with their obligatory partner Max, bind to E-boxes in target gene promoters and regulate the expression of 10-15% of all genes by the recruitment of different cofactors. READ MORE