Search for dissertations about: "Karolinska Institutet."

Showing result 1 - 5 of 311 swedish dissertations containing the words Karolinska Institutet..

  1. 1. Physiologically based modelling of nanoparticle biodistribution and biokinetics

    University dissertation from Stockholm : Karolinska Institutet, Institute of Environmental Medicine

    Author : Ulrika Carlander; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : To predict the toxicity of nanoparticles (1-100 nm), it is crucial to understand their biokinetics i.e. how they are taken up, distributed, dissolved and removed from the body. Such information can be gained from biodistribution studies in animals. READ MORE

  2. 2. The health economics of Duchenne muscular dystrophy

    University dissertation from Stockholm : Karolinska Institutet, Institute of Environmental Medicine

    Author : Erik Landfeldt; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Duchenne muscular dystrophy (DMD) is a rare neuromuscular disease characterized by progressive muscle degeneration resulting in loss of independent ambulation, serious multisystem complications, and a mean life expectancy at birth of about 25 years. Several therapies are on the horizon for DMD and it has thus become urgent to better understand the health economic context of the disease to enable assessments of cost-effectiveness and inform decisions regarding reimbursement of new health technologies. READ MORE

  3. 3. Nutritional factors and allergic disease : from infancy to adolescence

    University dissertation from Stockholm : Karolinska Institutet, Institute of Environmental Medicine

    Author : Jessica Magnusson; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Allergic disease is one of the most common non-communicable diseases in childhood. Both overweight and diet have been hypothesized to influence the risk of allergic disease. The aim of this thesis was to investigate the associations between overweight, fish intake and polyunsaturated fatty acids (PUFAs) and allergic disease throughout childhood. READ MORE

  4. 4. Worth weighting for : studies on benchmark dose analysis in relation to animal ethics in toxicity testing

    University dissertation from Stockholm : Karolinska Institutet, Institute of Environmental Medicine

    Author : Joakim Ringblom; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : A purpose of chemical health risk assessment is to characterize the nature and size of the health risk associated with exposure to chemicals, including identification of a dose below which toxic effects are not expected or negligible. This is usually based on analysis of dose- response data from toxicity studies on animals. READ MORE

  5. 5. Long-term exposure to air pollution from road traffic and lung function in children and adolescents

    University dissertation from Stockholm : Karolinska Institutet, Institute of Environmental Medicine

    Author : Erica S Schultz; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Lung function in early life is an important predictor of peak lung function and later decline in adults. However, lung development may also be influenced by factors later in childhood and adolescence. READ MORE