Search for dissertations about: "Katarina Edwards"

Showing result 1 - 5 of 13 swedish dissertations containing the words Katarina Edwards.

  2. 1. Vesicle - surfactant interactions : effect of non-ionic surfactants on structure and leakage of small unilamellar vesicles

    Author : Katarina Edwards; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  4. 2. Liposomes for Drug Delivery : from Physico-chemical Studies to Applications

    Author : Nill Bergstrand; Katarina Edwards; Felix M Goni; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; liposome; steric stabilisation; BNCT; cryo-TEM; EGF; targeting; stability; permeability; pH-sensitive liposomes; triggered release; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Abstract : Physico-chemical characterisation of structure and stability of liposomes intended for drug delivery is the central issue in this thesis. In addition, targeted liposomes to be used in boron neutron capture therapy (BNCT) were developed.Lysolipids and fatty acids are products formed upon hydrolysis of PC-lipids. READ MORE

  5. 3. Drug Partitioning into Natural and Artificial Membranes : Data Applicable in Predictions of Drug Absorption

    Author : Caroline Engvall; Birgitta Tomkinson; Katarina Edwards; Sven Engström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Bilayer disk; Cholesterol; Drug partitioning; Drugs; Electrostatic effects; Immobilized liposome chromatography; Liposome; Membrane protein; Model membrane; Oligonucleotide-liposome complex; Phospholipid; Phospholipid bilayer; Proteoliposome; Surfactant; Biokemi; Biochemistry; Biokemi;

    Abstract : When drug molecules are passively absorbed through the cell membrane in the small intestine, the first key step is partitioning of the drug into the membrane. Partition data can therefore be used to predict drug absorption. READ MORE

  6. 4. Enrichment and Separation of Phosphorylated Peptides on Titanium Dioxide Surfaces : Applied and Fundamental Studies

    Author : Anna I. K. Eriksson; Anders Hagfeldt; Katarina Edwards; Victor Agmo Hernández; Hubert Girault; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Posttranslational modification; Phosphorylation; Mass spectrometry; MALDI; Adsorption; QCM-D; Physical Chemistry; Fysikalisk kemi;

    Abstract : Protein phosphorylation is a very common posttranslational modification (PTM), which lately has been found to hold the keyrole in the development of many severe diseases, including cancer. Thereby, phosphoprotein analysis tools, generally based on specific enrichment of the phosphoryl group, have been a hot topic during the last decade. READ MORE

  7. 5. Effects of Ubiquinone-10 on the Stability and Mechanical Properties of Lipid Membranes

    Author : Emma K. Eriksson; Katarina Edwards; Victor Agmo Hernández; Emma Sparr; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ubiquinone-10; lipid bilayers; membrane stabilizer; liposome permeability; osmotic shock; cuvettes; solanesol; Chemistry with specialization in Physical Chemistry; Kemi med inriktning mot fysikalisk kemi;

    Abstract : Ubiquinones are a group of fat-soluble molecules present in many biological membranes. The most abundant version in humans, ubiquinone-10 (Q10), plays an important role in the mitochondrial respiration chain and also functions as a powerful antioxidant. Accumulating evidence suggests that Q10 also could have other functions in the membrane. READ MORE