Search for dissertations about: "Katarina Wide"

Showing result 1 - 5 of 17 swedish dissertations containing the words Katarina Wide.

  2. 1. Children exposed to antiepileptic drugs in utero : clinical and epidemiological aspects on growth, development and occurrence of malformations

    Author : Katarina Wide; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antiepileptic drugs (AED) are known teratogenic substances. Major congenital malformations, minor anomalies, retarded intrauterine growth and delayed psychomotor development have been reported after exposure to AED in utero. READ MORE

  4. 2. Defining the genetics of systemic autoimmunity in mouse models of lupus

    Author : Katarina Haraldsson; Kristina Lejon; Dwight Kono; Chandra Mohan; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SLE; susceptibility; HgIA; genome-wide mapping; Lbw2; Lmb1-4; suppressing gene; Immunology; Immunologi;

    Abstract : Systemic Lupus Erythematosus (SLE) is a chronic multi-organ autoimmune disease considered a prototype for autoantibody and immune complex-mediated tissue injury. Although autoantibodies against a wide diversity of self-antigens are characteristically found in this disease, an important hallmark is the presence of autoantibodies to nuclear antigens. READ MORE

  5. 3. Bioinformatics mining for disease causing mutations : using the dog genome as a model for human disease

    Author : Katarina Truvé; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Humans and dogs share many common diseases, and it has been shown that the identification of mutations that cause disease in dogs can help unravel the genetic basis for a similar disease in humans. Mapping of traits and disease in dogs is not a new idea, but the sequencing of the whole dog genome, the creation of a dense SNP maps followed by the development of SNP arrays for high throughput genotyping has led to new facilitated mapping procedures. READ MORE

  6. 4. Unraveling the genetics of lymphocytic thyroiditis using the dog as a model

    Author : Katarina Sundberg; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : The domestic dog, with its unique genetic structure formed by domestication and recent breed creation, has been proven to be an excellent model for mapping disease genes. In this thesis, we use the dog as a model to investigate the prevalence and genetic background of canine lymphocytic thyroiditis (CLT), one of the most common immune related diseases in dogs. READ MORE

  7. 5. Studies on the interaction of human cells with transplantable materials for skin repair and cardiovascular surgery

    Author : Katarina Jansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cell culture; Keratinocytes; Fibroblasts; Endothelial cells; Reepithelialization; In vitro endothelialization; Tissue engineering; Biomaterial: Dermal substitute; Synthetic vascular graft; Heart valve bioprosthesis;

    Abstract : Tissue engineering is becoming an important field for the development of new tissues in vitro for replacement of diseased or worn out parts of the body. This thesis describes some characteristics of cultured human cells seeded on transplantable materials for skin repair and cardiovascular surgery. READ MORE