Search for dissertations about: "Ki67"

Showing result 1 - 5 of 63 swedish dissertations containing the word Ki67.

  2. 1. The Columnar Lined Esophagus: aspects on the assessment of dysplasia and on the relationship with the esophageal submucosal glands

    Author : Ester Lörinc; Malmö Klinisk patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Columnar lined esophagus; Barrett´s esophagus; submucosal gland; multilayered epithelium; p53; Ki67; CK17; skin appendage;

    Abstract : Columnar metaplasia, where columnar epithelium replaces the normal squamous epithelium in esophagus, is considered to be a precancerous condition in which the development of adenocarcinoma can be followed through various grades of dysplasia. The interpretation of these histological changes is subjective and suffers from considerable inter-observer variation among pathologists. READ MORE

  4. 2. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

    Author : Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

    Abstract : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. READ MORE

  5. 3. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

    Author : Marie Klintman; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; predictive marker; resistance; prognostic factor; proliferation; prospective; TIMP-1; Ki67; S-phase; MAI; PPH3; cyclin B1; cyclin A; node-negative; validation;

    Abstract : Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. READ MORE

  6. 4. Epidermal keratinocytes studied by X-ray microanalysis, with special reference to contact dermatitis : In vivo and in vitro studies of functional changes in human cells

    Author : Anders Grängsjö; Uppsala universitet; []
    Keywords : Medical sciences; X-ray microanalysis; elements; epidermis; keratinocytes; proliferation; cell membrane damage; Ki67; irritants; intracellular elemental content; keratinocyte culture; HaCaT; NHEK; RT-PCR; immunohistochemistry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; anatomi; Human Anatomy;

    Abstract : By determining the intracellular elemental content, information can be obtained on the physiological status of cells. The cellular content of sodium, magnesium, phosphorus, sulfur, chloride, potassium and calcium can be indicative for proliferation, cell membrane damage or cell death. READ MORE

  7. 5. Refined diagnosis and prognosis in soft tissue sarcoma - genetic profiles, biomarkers and prognostic models

    Author : Ana Carneiro; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MFH; microarrays; prognostic factors; metastasis; local recurrence; proliferation; Ki67; Top2a; p21; p27; S-phase fraction; erzin.;

    Abstract : This work aimed at evaluate diagnosis and prognosis in soft tissue sarcoma (STS): In study I, 32K bacterial artificial chromosome (BAC) arrays and gene expression profiling were applied to 18 leiomyosarcomas and 31 undifferentiated pleomorphic sarcomas (UPS), with the aim of identifying molecular subtype signatures. Both the gains/losses profiles and the gene expression signatures revealed striking similarities between the two tumour types. READ MORE