Search for dissertations about: "Kristian Pietras"
Showing result 1 - 5 of 7 swedish dissertations containing the words Kristian Pietras.
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1. Inhibition of PDGF receptor signaling in tumor stroma : Effects on interstitial hypertension, drug uptake and therapeutic response
Abstract : The role of platelet-derived growth factor (PDGF) in malignancies involves both autocrine and paracrine stimulation of cells within the tumor. The interstitial fluid pressure (IFP) is one of the forces that govern the transvascular flow of fluids. READ MORE
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2. Leukocytes in Angiogenesis : Learning from Transplanted Pancreatic Islets
Abstract : Angiogenesis, the growth of new blood vessels, is a complex process involving several cell types and molecular signals. Excessive vascular growth is a problem in tumors, and insufficient vascularization hampers the function of transplanted insulin-producing pancreatic islets. READ MORE
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3. Cellular Origin and Development of Glioma
Abstract : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. READ MORE
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4. Type IV collagen in breast and colorectal cancer : a potential biomarker of metastatic disease
Abstract : Background: Metastatic colorectal cancer (mCRC) and metastatic breast cancer (mBC) are two leading causes of cancer-related mortality worldwide. Early detection of metastatic disease is critical, and sensitive, easily accessed and cost-effective biomarkers that can diagnose mBC and mCRC at an early stage would have high clinical value. READ MORE
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5. Tumor instructed normal tissue : studies of potential extratumoral biomarkers and therapeutic targets in prostate cancer
Abstract : Prostate cancer is the most common cancer in men in Sweden and but luckily the majority of the patients will carry on their life without any consequences from the disease. Unfortunately, some will develop aggressive tumors and eventually die. READ MORE