Search for dissertations about: "Kristin E Karlsson"
Found 2 swedish dissertations containing the words Kristin E Karlsson.
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1. Benefits of Pharmacometric Model-Based Design and Analysis of Clinical Trials
Abstract : Quantitative pharmacokinetic-pharmacodynamic and disease progression models are the core of the science of pharmacometrics which has been identified as one of the strategies that can make drug development more effective. To adequately develop and utilize these models one needs to carefully consider the nature of the data, choice of appropriate estimation methods, model evaluation strategies, and, most importantly, the intended use of the model. READ MORE
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2. Hearing problems in the elderly. Outsider and insider perspectives of presbyacusis
Abstract : What insight can be gained from an epidemiological perspective into factors affecting elderly people with hearing difficulties both individually and in relation to their surroundings? How is hearing impairment perceived by the elderly? How great is the need for audiological rehabilitation for elderly people with hearing impairments?Study I is a cross-sectional study within the framework of the age study H70 where a comparison was made between a) tone audiometry and self-assessments of hearing, b) tone audiometry and the prescription of hearing aids and c) self- assessments of hearing and the prescription of hearing aids. Three age cohorts were studied: 1) year of birth 1901-1902 (n=210: 133 f and 77 m), 2) year of birth 1915-16 (n=168: 94 f and 74 m) and 3) year of birth 1922-23 (n=237: 129 f and 108 m). READ MORE