Search for dissertations about: "L4-33K"

Found 3 swedish dissertations containing the word L4-33K.

  2. 1. The Adenovirus L4-33K Protein : A Key Regulator of Virus-specific Alternative Splicing

    Author : Heidi Törmänen Persson; Göran Akusjärvi; Stefan Schwartz; Marie Öhman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-33K; adenovirus; splicing; phosphorylation; localization; replication centers; L4-22K; MLTU; DNA-PK; DNA-dependent protein kinase; PKA; cAMP-dependent protein kinase; transcription sites; SR protein; Medical Virology; Medicinsk virologi;

    Abstract : Adenoviruses have been extensively studied in the field of gene regulation, since their genes are subjected to a tightly controlled temporal expression during the virus lifetime. The early-to-late shift in adenoviral gene expression distinguishes two completely different programs in gene expression. READ MORE

  4. 2. Functional Characterization of the Evolutionarily Conserved Adenoviral Proteins L4-22K and L4-33K

    Author : Sara Östberg; Göran Akusjärvi; Stefan Schwartz; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-22K; L4-33K; RNA; splicing; adenovirus; nuclear localization; replication; transcription; evolution; SR protein; MLP; promoter; E1A; serotypes;

    Abstract : Regulation of adenoviral gene expression is a complex process directed by viral proteins controlling a multitude of different activities at distinct phases of the virus life cycle. This thesis discusses adenoviral regulation of transcription and splicing by two proteins expressed at the late phase: L4-22K and L4-33K. READ MORE

  5. 3. Regulation of Adenoviral Gene Expression by the L4-33K and L4-22K Proteins

    Author : Ellenor Backström; Göran Akusjärvi; Francoise Raffalli-Mathieu; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virology; Virologi; Medical Virology; Medicinsk virologi;

    Abstract : The splicing pattern during an adenovirus infection is shifted at the late phase towards using weaker splice sites, splicing out larger introns. Splicing of weak 3´ splice sites usually requires recognition of the 3´AG dinucleotide before the first catalytic step of splicing. READ MORE