Search for dissertations about: "LNCaP"

Showing result 1 - 5 of 21 swedish dissertations containing the word LNCaP.

  2. 1. Prostasome Modulation of Blood Cascade System and Phosphoprotein Reactions with Focus on Prostate Cancer

    Author : Adil Abdelgadir Babiker; Kristina Nilsson Ekdahl; Michael Wilson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; ATPase; CD59; Complement; DU145; Extracellular phosphorylation; LNCaP; PC-3; Prostasomes; Prostate cancer; Protein kinases; Tissue factor; Immunologi; Immunology; Immunologi;

    Abstract : Prostasomes are extracellularly occurring submicron, membrane-surrounded organelles produced by the epithelial cells of the prostate and present in semen. Their precise physiological role is not known, although some of their properties assign them to important physiological and patho-physiological functions. READ MORE

  4. 2. Phytoestrogens and prostate cancer : experimental, clinical, and epidemiological studies

    Author : Annika Bylund; Pär Stattiin; Anders Bergh; Göran Hallmans; Swen-Olof Andersson; Umeå universitet; []
    Keywords : prostatic neoplasm; phytoestrogens; lignans; enterolactone; rye; 7-hydroxymataireorcinol; nude mice; TRAMP mice; nested case control study; LNCaP; Oncology; onkologi;

    Abstract : Dietary factors may affect development and progression of prostate cancer. Experimental and epidemiological studies have suggested an effect of phytoestrogens on prostate cancer. Lignans are the predominant phytoestrogen in a Western diet. READ MORE

  5. 3. Regulation of Vitamin D 25-hydroxylases : Effects of Vitamin D Metabolites and Pharmaceutical Compounds on the Bioactivation of Vitamin D

    Author : Maria Ellfolk; Kjell Wikvall; Maria Norlin; Olavi Pelkonen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP2D25; vitamin D 25-hydroxylase; transcriptional regulation; vitamin D; CYP2R1; CYP2J2; CYP27A1; phenobarbital; efavirenz; fibroblast; LNCaP; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Abstract : A 700bp portion of the promoter of CYP2D25, the porcine microsomal vitamin D 25-hydroxylase was isolated and sequenced. The computer analysis of the sequence revealed the existence of a putative VDRE at 220 bp upstream of the transcription start site. READ MORE

  6. 4. Androgen-Independent Prostate Cancer - studies on angiogenesis and ADAMTS1

    Author : Helene Gustavsson; Göteborgs universitet; []
    Keywords : Prostate cancer; Androgen-independent; Castration resistant; Hormone refractory; Angiogenesis; Microvessel density; ADAMTS1; LNCaP; VEGF; TSP1;

    Abstract : Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer since prostate tumors initially are dependent on androgens for growth. However, most tumors will eventually relapse and grow in a highly aggressive and androgen-independent (AI) manner. READ MORE

  7. 5. Tissue prostatic specific antigen (T-PSA) : a way to predict and understand the development of prostate cancer

    Author : Mirtha Grande; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tissue PSA; aspiration biopsies; estrogens; ecNOS mRNA expression; ET1 mRNA expression; LNCaP-FGC; LNCaP-r.;

    Abstract : Prostate cancer (CaP) is the most prevalent malignancy among men in Sweden. One major problem associated with CaP is the choice of treatment since the disease may develop very differently from patient to patient. Many efforts have focused on the development of markers for prognosis and monitoring treatment affecting the endocrine system of CaP. READ MORE