Search for dissertations about: "Left Ventricular drug therapy pathology"

Found 1 swedish dissertation containing the words Left Ventricular drug therapy pathology.

2. 1. Pharmacogenomics of Antihypertensive Treatment & Clinical Pharmacological Studies of Digoxin Treatment

   Author : Pär Hallberg; Håkan Melhus; Ann-Christine Syvänen; Lars Lind; Jiguang Wang; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; pharmacogenomics; irbesartan; atenolol; hypertension; digoxin; RIKS-HIA; atrial fibrillation; heart failure; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ;

   Abstract : In Part I we found that the CYP2C9 genotype appears to influence the diastolic blood pressure response to the angiotensin II-receptor antagonist irbesartan in patients with hypertension and left ventricular hypertrophy. Those with the *1/*2 genotype (slower metabolism) responded better than those with the *1/*1 genotype (normal metabolism), likely due to a slower elimination of the drug. READ MORE