Search for dissertations about: "Leukocyte drug effects"
Showing result 1 - 5 of 14 swedish dissertations containing the words Leukocyte drug effects.
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1. Effects of high glucose on platelet activation
Abstract : Diabetes mellitus (DM) is associated with increased cardiovascular mortality and morbidity, due to diabetic angiopathy. Hyperglycaemia is one of the factors that may cause platelet dysfunction in diabetic patients. This work investigated the mechanisms underlying hyperglycaemia-induced platelet hyperreactivity and its impact in diabetic patients. READ MORE
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2. Anti-drug antibodies in patients with multiple sclerosis
Abstract : Multiple sclerosis (MS) is an inflammatory disease affecting the brain and spinal cord and it is the main cause of neurological disability among young adults. Recombinant interferon beta (IFNβ) and natalizumab are commonly used disease-modifying drugs that reduce disease severity. READ MORE
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3. Pharmacometric Models for Improved Prediction of Myelosuppression and Treatment Response in Oncology
Abstract : Chemotherapy plays an important role in the treatment of cancer. However, these drugs also cause death of non-malignant cells, resulting in severe side-effects. In addition, drug resistance may exist. Predictive tools for dose and drug selection are therefore warranted. READ MORE
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4. Pleurodesis in chronic effusions : studies on inflammatory mediators, respiratory function, predictability of treatment outcome, drug efficiency and survival after treatment
Abstract : Metastatic or primary (mesothelioma) malignancy of the pleura often generates major pleura] effusion, giving respiratory distress and low quality of life to the patients. Evacuation of fluid by thoracocentesis gives only temporary relief, therefore pleurodesis is generally regarded the best way to give palliation. READ MORE
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5. Psychosocial factors and immune parameters during cancer chemotherapy
Abstract : Cancer patients are exposed to side-effects during chemotherapy, such as nausea and vomiting elicited by drug administration, or in anticipation of treatment. Chemotherapy also results in bone marrow suppression. READ MORE