Search for dissertations about: "Lipoprotein Lipase metabolism"
Showing result 1 - 5 of 32 swedish dissertations containing the words Lipoprotein Lipase metabolism.
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1. Regulation of Lipoprotein Lipase Activity : an In-vitro Study of a Complex and Dynamic System
Abstract : The progress of human society outpaces our biological evolution, and this brings unexpected health problems. The industrial revolution brought up dramatic changes in nutrition and lifestyle – we are increasingly shifting towards a nutrient-rich Western-patterned diet and to a sedentary lifestyle. READ MORE
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2. Lipoprotein lipase-unstable on purpose?
Abstract : Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. It is a non-covalent, homodimeric and N-glycosylated protein, which is regulated in a tissue-specific manner and is dependent on an activator protein, apolipoprotein CII. Dissociation of active LPL dimers to monomers leads to loss of activity. READ MORE
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3. Angiopoietin-like protein 4 : an unfolding chaperone regulating lipoprotein lipase activity
Abstract : Lipoprotein lipase (LPL) is the main enzyme hydrolyzing triglyceride-rich lipoproteins in plasma. Proteoglycan-bound LPL on the vascular endothelium represent the functional pool of active enzyme. LPL is regulated in a tissue specific manner according to metabolic demands. READ MORE
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4. Lipoprotein lipase in hemodialysis patients and healthy controls : effects of heparin
Abstract : Mortality from cardiovascular disease in patients on chronic hemodialysis (HD) is 10 to 20 times greater than in the general population. One major risk factor is renal dyslipidemia, characterised by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. READ MORE
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5. Endogenous and exogenous factors affecting lipoprotein lipase activity
Abstract : Individuals with high levels of plasma triglycerides are at high risk to develop cardiovascular disease (CVD), currently one of the major causes of death worldwide. Recent epidemiological studies show that loss-of-function mutations in the APOC3 gene lower plasma triglyceride levels and reduce the incidence of coronary artery disease. READ MORE