Search for dissertations about: "Liposomes"

Showing result 6 - 10 of 114 swedish dissertations containing the word Liposomes.

  2. 6. Hyperthermia-responsive liposomal systems

    Author : Yujia Jing; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cationic lipid; asymmetry; phospholipase; liposomes; flip-flop; hyperthermia; phase transition; supported lipid membranes; drug delivery;

    Abstract : Abstract Sophisticated liposomal systems are emerging at an increasing rate to meet the demands for multifunctional drug carriers in chemotherapies in combined with hyperthermia. For example, liposomal drug carriers for temperature-controlled drug release under hyperthermic conditions have recently been tested in clinical trials. READ MORE

  4. 7. Quantitative Aspects of Nanodelivery Across the Blood-Brain Barrier : Exemplified with the Opioid Peptide DAMGO

    Author : Annika Lindqvist; Margareta Hammarlund-Udenaes; Markus Fridén; William Elmquist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood-brain barrier; liposomes; nanocarriers; brain delivery; pharmacokinetics; modeling and simulation; microdialysis; opioid peptide; DAMGO; LC-MS MS; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : The use of nanocarriers is an intriguing approach in the development of efficacious treatment for brain disorders. The aim of the conducted research was to evaluate and quantify the impact of a liposomal nanocarrier formulation on the brain drug delivery. READ MORE

  5. 8. Effects of gangliosides and PEG-lipids on the structure, properties and interactions of lipid self-assemblies

    Author : Philipp Grad; Katarina Edwards; Marité Cárdenas; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lipid self-assemblies; solution-solid interface; liposomes; lipodisks; lipid bilayers; liposome permeability; cuvettes;

    Abstract : When developing or utilizing lipid-based nanocarriers detailed structural characterization of the lipid self-assemblies, as well as in depth knowledge and control of their interaction with solids materials, is necessary to understand the behaviour. Disregarding one of the parameters can lead to misinterpretation of the results due to non-uniform samples or experimental artifacts caused by undesirable interactions with solid surfaces. READ MORE

  6. 9. Synthesis and Applications of Dynamic Multivalent Nanostructures

    Author : Kitjanit Neranon; Olof Ramström; Aldrik Velders; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; multivalent nanostructures; self-assembly; metal-ligand exchange; dynamic covalent chemistry; bipyridine derivatives; dendrimers; liposomes; drug delivery; antimicrobial materials; fluorescent probe; plasmonic chemistry; gold surface functionalization; Kemi; Chemistry;

    Abstract : This thesis focuses on the design, synthesis and development of dynamic multivalent nanostructures such as supramolecular dendrimers, liposomes and gold-functionalized nanostructures. These structures can be used for drug delivery and molecular sensing applications. READ MORE

  7. 10. Studying the influence of the physicochemical properties of lipid nanoparticles for mucosal vaccine delivery

    Author : Karin Norling; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; influenza; nanoparticles; CTA1-DD; liposomes; dendritic cells; lipodisks; antigen presentation; flow cytometry; vaccine carriers; TIRF microscopy;

    Abstract : Lipid-based nanoparticles have attracted attention as promising pharmaceutical carriers. Reports of them having inherent adjuvant properties make them particularly interesting as vaccine vectors; however, the physicochemical profile of an ideal nanoparticle for mucosal vaccine delivery remains unknown. READ MORE