Search for dissertations about: "Lucia Mincheva-Nilsson"

Showing result 1 - 5 of 11 swedish dissertations containing the words Lucia Mincheva-Nilsson.

2. 1. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

   Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

   Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE

4. 2. The role of natural killer cells and inflammatory mediators in preeclamptic pregnancies

   Author : Nora Bachmayer; Eva Sverremark-Ekström; Katarina Bremme; Lucia Mincheva-Nilsson; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; preeclampsia; NK cells; Immunology; Immunologi; immunologi; Immunology;

   Abstract : The maternal immune system must be able to adjust during pregnancy and accept the foetus that expresses paternal antigens. These changes are found both in placenta and circulation, including a mild inflammatory response. NK cells are abundant during the early part of pregnancy in placenta and are thought to be important for placental development. READ MORE

5. 3. Prostasomes as Diagnostic, Prognostic and Therapeutic Vesicles

   Author : Louise Dubois; Anders Larsson; Lucia Mincheva-Nilsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exosomes; Prostasomes; Lipid rafts; Bioengineered vesicles; Prostate cancer; Purinergic receptors; Thymidine kinase 1; Medical Biochemistry; Medicinsk biokemi;

   Abstract : This thesis explores prostasomes and their ability to be used as a new diagnostic tool for prostate cancer. Alongside diagnosis, this thesis also suggests prostasomes as a tool for prognosis and therapeutic treatment in patients with prostate cancer. READ MORE

6. 4. Exosomes and the NKG2D receptor-ligand system in pregnancy and cancer : using stress for survival

   Author : Malin Hedlund; Lucia Mincheva-Nilsson; Susanne Gabrielsson; Umeå universitet; []
   Keywords : Exsosomes; NKG2D; MICA; MICB; ULBP; human placenta; trophoblast; syncytiotrophoblast; thermal stress; oxidative stress; leukemia; lymphoma; immunologi; Immunology;

   Abstract : Although not obvious at first sight, several parallels can be drawn between pregnancy andcancer. Many proliferative, invasive and immune tolerance mechanisms that supportnormal pregnancy are also exploited by malignancies to establish a nutrient supply andevade or edit the immune response of the host. READ MORE

7. 5. Mechanisms for immune escape in epithelial ovarian cancer

   Author : Pernilla Israelsson; Ulrika Ottander; Lucia Mincheva-Nilsson; Eva Lundin; Ivan Nagaev; Karin Sundfeldt; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; ovarian cancer; high-grade serous cancer; EOC; HGSC; HGSOC; tumor microenvironment; immune escape; immune suppression; cytokines; exosomes; NKG2D; MICA B; ULBP1-3; DNAM-1; surgery; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Abstract : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. READ MORE