Search for dissertations about: "Lymphangiogenesis and lymphatic metastasis"

Showing result 1 - 5 of 6 swedish dissertations containing the words Lymphangiogenesis and lymphatic metastasis.

  1. 1. Lymphangiogenesis and lymphatic metastasis

    Author : Meit A Björndahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Angiogenesis; lymphangiogenesis; lymphatic metastasis; PDGF; IGF; VEGF-A;

    Abstract : The major cause of cancer mortality is metastasis, which relies on the growth of blood vessels (haemangiogenesis) and lymphatic vessels (lymphangiogenesis). Whereas the field of haemangiogenesis has been relatively thoroughly studied, little is known about the mechanisms regulating lymphangiogenesis. READ MORE

  2. 2. Hem- and lymph-angiogenesis in cancer metastasis

    Author : Hong Ji; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Angiogenesis, the process of sprouting new microvessels from the preexisting vasculature, is known to promote tumor growth. However, the role of tumor angiogenic vessels in facilitating metastasis remains poorly understood. READ MORE

  3. 3. The role of VEGF family in angiogenesis, tumor growth and metastasis

    Author : Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. READ MORE

  4. 4. Mechanisms of tumor microenvironment in promoting metastasis

    Author : Patrik Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor tissues contain diverse cell populations that relentlessly cross-communicate with each other in the tumor microenvironment. In addition to malignant cells, infiltration of other host cells including inflammatory cells, fibroblasts, and cells in the vessel walls in tumors significantly contribute to tumor growth and metastasis. READ MORE

  5. 5. Human colorectal cancer : experimental staging and therapeutics

    Author : Kjell Dahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Colorectal cancer is the third most common cause of death in cancer worldwide and approximately one million individuals are diagnosed yearly. Surgery is the primary cure, and if that s not feasible, only palliative therapy remains. Colorectal cancer disseminates into peritumoral lymphatic vessels and further into the regional lymph nodes. READ MORE