Search for dissertations about: "M1 macrophage"
Showing result 1 - 5 of 20 swedish dissertations containing the words M1 macrophage.
-
1. Functional properties of galectin-3. Beyond the sugar binding
Abstract : Contemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. READ MORE
-
2. Metabolic and immunological interactions between adipose tissue and breast cancer - implications of obesity in tumor progression
Abstract : Triple-negative breast cancers have fewer treatment options than other breast cancers. The overall goal of this research is to identify new pharmaceutical targets for triple-negative breast cancer through studies of the tumor-promoting crosstalk between tumor and surrounding adipose tissue. READ MORE
-
3. Streptococcus pyogenes : life within the macrophage
Abstract : Streptococcus pyogenes is a versatile human pathogen causing a wide array of diseases ranging from uncomplicated throat and skin infections to invasive life- threatening diseases with a mortality rate of up to 60%. It is ranked number nine on the list of worst infectious diseases world wide, causing 500 000 deaths yearly. READ MORE
-
4. Macrophage programming and host responses to bacterial infection
Abstract : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. READ MORE
-
5. Cancer and Inflammation : Role of Macrophages and Monocytes
Abstract : Macrophages are cells of the innate immune system that can be found in large quantities in cancer tumors and affect cancer progression by regulating growth and invasiveness of cancer cells. There are two main phenotypes of macrophages denoted M1 and M2. READ MORE