Search for dissertations about: "MC1R"

Showing result 1 - 5 of 12 swedish dissertations containing the word MC1R.

2. 1. Mapping Genes Affecting Phenotypic Traits in Chicken

   Author : Susanne Kerje; Leif Andersson; Martien Groenen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; chicken; Quantitative Trait Loci; growth; egg production; epistasis; plumage colour; Extended black; MC1R; Dominant white; PMEL17; Genetik; Clinical genetics; Klinisk genetik;

   Abstract : The purpose of gene mapping is to understand the underlying genetics of simple and complex traits like plumage colour and growth. This thesis is based on a cross between the wild ancestor of the modern chicken, the red junglefowl, and a White Leghorn line selected for high egg mass. READ MORE

4. 2. Arrayed identification of DNA signatures

   Author : Max Käller; Lundeberg Joakim; Mats Nilsson; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; apyrase; allele-specific extension; competitive hybridization; DNA sequencing; genotyping; human papillomavirus HPV ; MC1R; microarray; mutation; p53; protease; Bioengineering; Bioteknik;

   Abstract : In this thesis techniques are presented that aim to determine individual DNA signatures by controlled synthesis of nucleic acid multimers. Allele-specific extension reactions with an improved specificity were applied for several genomic purposes. Since DNA polymerases extend some mismatched 3’-end primers, an improved specificity is a concern. READ MORE

5. 3. The genetic basis for adaptation in natural populations

   Author : Sangeet Lamichhaney; Leif Andersson; Carl-Johan Rubin; Alvaro Martinez Barrio; Henrik Kaessmann; Uppsala universitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Adaptive evolution; Atlantic herring; ecological adaptation; seasonal reproduction; TSHR; Darwin’s finches; natural selection; beak; ALX1; HMGA2; ruff; lek; inversion; HSD17B2; MC1R;

   Abstract : Many previous studies in evolutionary genetics have been based on few model organisms that can be reared at ease in the laboratory. In contrast, genetic studies of non-model, natural populations are desirable as they provide a wider range of adaptive phenotypes throughout evolutionary timescales and allow a more realistic understanding of how natural selection drives adaptive evolution. READ MORE

6. 4. Hybrid zones and speciation – insights from the European crow hybrid zone

   Author : Fredrik Haas; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; microsatellites; mc1r; introgression; hybrid zone; speciation; European crow; Corvus corone; habitat preferences; neural network; sexual imprinting; assortative mating;

   Abstract : In hybrid zones genetically differentiated populations meet and interbreed. As they result from ongoing divergence and potential speciation, such zones provide opportunities to study how different factors affect this process. The hybrid zone between the all black carrion crow (Corvus corone corone) and the grey and black hooded crow (Corvus c. READ MORE

7. 5. Podocyte Melanocortin 1 Receptor Mediated Signaling : A potential new target for patients with kidney diseases

   Author : Johannes Elvin; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Podocyte; Melanocortin 1 Receptor; actin cytoskeleton; nephrotic syndrome; adrenocorticotropic hormone; oxidative stress; RhoA; Kidney disease;

   Abstract : Treatment of patients with nephrotic syndrome (NS) is currently unspecific and directed at ameliorating the symptoms rather than eliminating the cause. NS is actually a multitude of glomerular diseases characterized by poorly understood disease mechanisms and symptoms that include proteinuria, hypoalbuminemia and edema. READ MORE