Search for dissertations about: "MEDICINE Physiology and pharmacology Physiology Clinical physiology"

Showing result 1 - 5 of 6 swedish dissertations containing the words MEDICINE Physiology and pharmacology Physiology Clinical physiology.

2. 1. Vascular effects of neuropeptides and UDP-β-S and alterations after stroke

   Author : André Erdling; Neurokirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The aim of this thesis is to investigate the changes in vasoactive intestinal peptide (VIP) and calcitonin gene-related peptide(CGRP) and P2Y6-mediated signaling following experimental subarachnoid hemorrhage (SAH) and transient middle cerebral artery occlusion (tMCAO). VIP and CGRP are among the most powerful vasodilators known to man while P2Y6 mediates strong vasoconstriction in cerebral blood vessels. READ MORE

4. 2. Brain glycine receptors as a common target for alcohol and the relapse-preventing drug acamprosate - a preclinical study

   Author : Pei Pei Chau; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alcoholism; Acamprosate; Glycine receptor; Preclinical study; Dopamine; Ethanol;

   Abstract : Alcohol abuse and dependence make up the most prevalent categories of substance use disorders in the world. Converging evidence from the current research group has identified two receptor populations, the glycine (GlyRs) and nicotinic acetylcholine receptors (nAChRs) in the mesolimbic dopamine system, as two potentially important targets for the development of new medication to treat alcohol dependence. READ MORE

5. 3. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain

   Author : Catarina Lindquist; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Fysiologi; Ion channels; GABA; Inhibition;

   Abstract : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). READ MORE

6. 4. Optimizing nicotinic acid delivery for durable antilipolysis and improved metabolic control

   Author : Tobias Kroon; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Type 2 diabetes is a devastating disease affecting hundreds of millions worldwide. Lipid accumulation in peripheral non-adipose tissues is a major driver of insulin resistance, a central pathophysiological defect of this disease. READ MORE

7. 5. Blood Flow in Human Skeletal Muscle : The Effect of Adrenaline and the Influence of a Small Muscle Injury

   Author : Torbjörn Vedung; Jan Henriksson; Jan Lundvall; Södersjukhuset Karolinska Institutet. Dept of Hand Surgery Dept of Physiology and Pharmacology; Karolinska Institutet; Karolinska Institutet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adrenaline; blood flow; blood redistribution; ischemia; muscle injury; skeletal muscle; strain-gauge plethysmography; sympathetic tone; transmural pressure; 99mTechnetium clearance; tennis elbow; venous compliance; venous occlusion plethysmography; 133Xenon clearance; adrenaline;

   Abstract : A variety of vasoregulatory systems are involved in the complex control of blood flow inhuman skeletal muscle. The interaction between these systems where one system canoverride or modify the other makes blood flow regulation complicated. READ MORE