Search for dissertations about: "MUC5AC"
Showing result 1 - 5 of 11 swedish dissertations containing the word MUC5AC.
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1. Helicobacter pylori adhesion and patho-adaptation : the role of BabA and SabA adhesins in persistent infection and chronic inflammation
Abstract : Helicobacter pylori (H. pylori) is a human-specific gastric pathogen which is responsible for a spectrum of diseases ranging from superficial gastritis to gastric and duodenal ulceration, and which is also highly associated with gastric cancer. The pathogenesis of severe gastric disorders caused by H. READ MORE
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2. Assembly and proteolytic cleavages of gel-forming mucins
Abstract : Gel-forming mucins are large glycoproteins constituting the main structural component of themucus layer protecting epithelial surfaces of the body. This thesis aims to a deeper understandingof how gel-forming mucins are synthesized and assembled, and how they may interact with othermolecules. READ MORE
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3. Sensory mechanisms in the human upper airway - Role of TRP ion channels
Abstract : The nasal mucosa is richly innervated with sensory nerves having the ability to detect changes in the environment and mediate symptoms such as secretion and itch. Some TRP ion channels such as TRPV1 and TRPA1 are abundantly expressed in sensory nerves and respond to a wide variety of stimuli, including irritants, inflammatory mediators and temperatures. READ MORE
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4. Early stage inflammation and cancer as reflected in the gastrointestinal mucus composition: implications for diagnosis, prognosis and pathogenesis
Abstract : Mucus covers our inner interfaces towards the environment, providing protection while enabling vital interaction with the outside world. The mucus is built around mucin proteins, which are important for our defences against infection and inflammation, but may also contribute to carcinogenesis and tumour progression. READ MORE
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5. Aiway Mucins: experimental models for studies of secretions
Abstract : Mucins are essential components of the mucosal barrier. The complexity of the airway mucosal barrier is reflected in the lack of specific treatments to block mucin hypersecretion associated with several respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis. READ MORE