Search for dissertations about: "Macrophage Activation"

Showing result 1 - 5 of 134 swedish dissertations containing the words Macrophage Activation.

  2. 1. Mycobacterium tuberculosis and the human macrophage : shifting the balance through inflammasome activation

    Author : Daniel Eklund; Maria Lerm; Olle Stendahl; Eva Särndahl; Norbert Reiling; Linköpings universitet; []
    Keywords : ;

    Abstract : Mycobacterium tuberculosis is a very successful pathogen and tuberculosis constitutes a major threat to global health worldwide. The World Health Organization (WHO) estimates that almost nine million new cases and 1. READ MORE

  4. 2. Signal Transduction in Malignant Cells – Transformation, Activation and Differentiation

    Author : Karin Kårehed; Fredrik Öberg; Jan-Ingvar Jönsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; transformation; PDGF; PI3K; Rho-GTPase; U-937; FcγRI; macrophage; Stat1; PKR; NFκB; ATRA; differentiation; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Pathology; Patologi;

    Abstract : All aspects of cell life are regulated by signal transduction mechanisms. This thesis describes the regulatory roles of a few key signal transduction molecules involved in three major biological responses. READ MORE

  5. 3. Intracellular lipids and inflammatory activity in macrophage foam cells

    Author : Jenny Persson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; lipid droplet; cytokine; inflammation; adipophilin; perilipin; atherosclerosis; Macrophage; foam cell;

    Abstract : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. READ MORE

  6. 4. Macrophage Activation and AP-1 in Atherosclerosis

    Author : Maria Stollenwerk; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Proteins; enzymology; Proteiner; enzymologi; Cardiovascular system; carotid plaque; interleukin-1b; caspase-1.; very low-density lipoprotein; fatty acids; activator protein-1; inflammation; Atherosclerosis; nuclear factor-kB; macrophages; tumor necrosis factor;

    Abstract : High levels of very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease. Hypertriglyceridemia is generally associated with an increased expression of inflammatory makers and inflammation is thought to contribute to atherosclerosis and its complications. READ MORE

  7. 5. The importance of monocyte and granulocyte activation in rheumatoid arthritis and primary Sjögren's syndrome

    Author : Ingunn Torsteinsdóttir; Uppsala universitet; []
    Keywords : Medical sciences; Rheumatoid arthritis; primary Sjögren s syndrome; peripheral blood; monocyte; macrophage; neutrophil; eosinophil; adhesion; phagocytosis; respiratory burst; CRP; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Abstract : Macrophages and neutrophils infiltrate the synovium and synovial fluid in rheumatoid arthritis (RA). These cells are considered to contribute to the destructive process in RA.The expression of adhesion and phagocytosis receptors on the surface of peripheral granulocytes and monocytes was increased in patients with RA. READ MORE