Search for dissertations about: "Macrophages microbiology"

Showing result 1 - 5 of 41 swedish dissertations containing the words Macrophages microbiology.

  2. 1. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Author : Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Abstract : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. READ MORE

  4. 2. Macrophage programming and host responses to bacterial infection

    Author : Xiao Wang; Hong Sjölinder; Martin Rottenberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Macrophages; meningococci; mycobacteria; NhhA; CD46; cytokines; molekylärgenetik; Molecular Genetics;

    Abstract : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. READ MORE

  5. 3. Host-bacteria interactions : Host cell responses and bacterial pathogenesis

    Author : Nele de Klerk; Ann-Beth Jonsson; Teresa Frisan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Host-bacteria interaction; Helicobacter pylori; Neisseria gonorrhoeae; Lactobacillus; Epithelial cells; Macrophages; EGR1; Amphiregulin; SabA; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Helicobacter pylori colonizes the human stomach, where it causes gastritis that may develop into peptic ulcer disease or cancer when left untreated. Neisseria gonorrhoeae colonizes the urogenital tract and causes the sexually transmitted disease gonorrhea. READ MORE

  6. 4. Evolution and host-specific adaptations of Legionella pneumophila

    Author : Anaísa B. Moreno; Lionel Guy; Dan I. Andersson; Fredrik Söderbom; Alexander W. Ensminger; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Evolution; Legionella pneumophila; host-adaptation; experimental evolution; Acanthamoeba castellanii; transfection; Mikrobiologi; Microbiology;

    Abstract : How bacteria evolve pathogenic traits is shaped by their communities and environments. Legionella pneumophila is ubiquitous in aquatic habitats, where it persists by replicating within a broad range of protozoan hosts. Using the same mechanisms, L. READ MORE

  7. 5. Immune modulation of macrophages by the meningococcal surface protein NhhA

    Author : Xiao Wang; Hong Sjölinder; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Functional immune modulation of macrophages play important role during bacterial infection. Neisseria meningitidis, a gram-negative diplococcal bacterium, is the leading cause of bacterial meningitis and fatal septic shock. However, it is also a commensal bacterium that colonizes the nasopharynx of healthy individuals asymptomatically. READ MORE