Search for dissertations about: "Malformation"

Showing result 1 - 5 of 81 swedish dissertations containing the word Malformation.

  2. 1. 12-14 week scan with emphasis on risk assessment for fetal structural malformations and fetal loss

    Author : Maria-Dorothea Westin; gynekologisk och prenatal ultraljudsdiagnostik Obstetrisk; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet; reproduction; sexuality; Obstetrics; gynaecology; andrology; Miscarriage; Malformation; Congenital cardiac defect; Nuchal translucency; Prenatal diagnosis; Medicin människa och djur ; Medicine human and vertebrates ; Risk assessment;

    Abstract : The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. READ MORE

  4. 2. The Role of the SHB Adapter Protein in Cell Differentiation and Development

    Author : Vitezslav Kriz; Michael Welsh; Urban Lendahl; Uppsala universitet; []
    Keywords : Cell biology; SHB; transgene; ES cells; cavitation; knockout; mouse; vasculogenesis; hematopoiesis; endoderm; mesoderm; malformation; Cellbiologi;

    Abstract : The present study was conducted in order to assess a role of the SH2 domain-containing adapter protein SHB in development and cell differentiation.Embryonic stem (ES) cells overexpressing SHB and SHB with an inactive SH2 domain (R522K-SHB) were obtained. READ MORE

  5. 3. Developmental disturbances of the embryo in diabetic pregnancy

    Author : Parri Wentzel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; diabetes; pregnancy; embryo; malformation; glucose; ROS; SOD; NAC; prosta- glandin; COX; COX inhibitor; gene expression; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Maternal diabetes during pregnancy constitutes an increased risk for congenital malformation in the offspring. Previous studies have suggested that diabetic embryopathy is associated with an excess of reactive oxygen species (ROS) as well as with a disturbance of prostaglandin (PG) metabolism. READ MORE

  6. 4. Maternal smoking and congenital malformations

    Author : Karin Källén; Tornbladinstitutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratologi; Utvecklingsbiologi; embryology human ; ontogeny; Epidemiology; smoking; malformation; pregnancy; registry; confounders; teratology; Development biology; embryologi människa ;

    Abstract : About two percent of Swedish newborn infants are born with a significant congenital malformations which is reported to the Swedish Registry of Congenital Malformations (RCM), and/or the Swedish Medical Birth Registry (MBR). In spite of persistent public health recommendations, about 16% of the Swedish pregnant women are smoking during pregnancy (1996). READ MORE

  7. 5. Inflammation and immunothrombosis in cerebral cavernous malformation : Novel molecular targets for the treatment of an incurable disease

    Author : Maria Ascención Globisch; Peetra Magnusson; Elisabetta Dejana; Marie Jeansson; Anna Randi; Uppsala universitet; []
    Keywords : Cavernoma; Inflammation; Coagulation; Blood-brain-barrier; Blood; Hypoxia; Propranolol; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

    Abstract : Cerebral cavernous malformation (CCM) is a vascular disease that causes mulberry-like lesions (cavernomas) in the central nervous system (CNS). Cavernomas are fragile, leaky and prone to rupture which may cause symptoms such as epileptic seizures, focal neurological deficits and hemorrhagic strokes. CCM lesions can appear sporadically in 0. READ MORE