Search for dissertations about: "Malignant"

Showing result 1 - 5 of 1031 swedish dissertations containing the word Malignant.

2. 1. Malignant glioma : experimental studies with an estrogen-linked cytostatic

   Author : Eva von Schoultz; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; malignant glioma; meningioma; glioma cells; sex steroids; estramustine; nor-nitrogen mustard; estramustine- binding protein; DNA damage; cell membrane;

   Abstract : Malignant gliomas are the most common primary brain tumors in adults. Patients with these highly malignant tumors have an extremely poor prognosis. The situation with a highly proliferative tumor in a non-proliferating tissue should favor cytostatic treatment but so far the role of conventional chemotherapy has been adjunctive. READ MORE

4. 2. Prognostic Factors in Malignant Melanoma

   Author : Åsa Bolander; Michael Bergqvist; Simon Ekman; Anders Larsson; Daniel Brattström; Gunnar Wagenius; Torgny Rasmuson; Uppsala universitet; []
   Keywords : Malignant melanoma; prognostic factors; survival; chemotherapy; radiation;

   Abstract : Because of the failure so far to find effective treatment for patients with advanced stages of melanoma, increasing efforts have been made to find prognostic factors identifying patients in the risk zone for development of metastasis.This thesis investigates the prognostic powers of a few selected serological and immunohistochemical biomarkers. READ MORE

5. 3. Biomarker Discovery in Cutaneous Malignant Melanoma : A Study Based on Tissue Microarrays and Immunohistochemistry

   Author : Margrét Agnarsdóttir; Fredrik Ponten; Peter Naredi; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody-based proteomics; automated analysis; biomarker; immunohistochemistry; malignant melanoma; survival; tissue microarray; Tumour biology; Tumörbiologi; Pathology; Patologi; Molecular medicine; Molekylär medicin; Medical Science; Medicinsk vetenskap; Pathology; Patologi;

   Abstract : The incidence of cutaneous malignant melanoma has increased dramatically in Caucasians the last few decades, an increase that is partly explained by altered sun exposure habits. For the individual patient, with a localized disease, the tumor thickness of the excised lesion is the most important prognostic factor. READ MORE

6. 4. Malignant melanoma in Sweden : occurrence, prognostic factors and time trends

   Author : Magnus Thörn; Uppsala universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : .... READ MORE

7. 5. Associations Between Rheumatoid Arthritis and Malignant Lymphomas

   Author : Eva Baecklund; Christer Sundström; Anders Ekbom; Roger Hällgren; Tore Kvien; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; rheumatoid arthritis; malignant lymphoma; diffuse large B-cell lymphoma; disease activity; disease modifying anti-rheumatic drug; Epstein-Barr virus; germinal centre-like non-germinal centre-like subtype; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Abstract : Patients with rheumatoid arthritis (RA) are at increased risk of developing malignant lymphoma, although details about this association remain unclear. The aims of this thesis were to investigate risk factors for lymphoma in patients with RA and to characterize these lymphomas regarding subtype, presence of Epstein-Barr virus (EBV), clinical manifestations and prognosis. READ MORE