Search for dissertations about: "Malin Gustavsson"

Found 2 swedish dissertations containing the words Malin Gustavsson.

2. 1. Design of enzymatic systems for the modification of cellulose fiber surfaces

   Author : Malin Gustavsson; KTH; []
   Keywords : Candida antarctica lipase B; Pichia pastoris; cellulose-binding module; proteolysis; carbohydrate ester; xyloglucan endotransglycosylase; fiber modification;

   Abstract : This thesis describes the design of enzymatic systems forthe modification of cellulose fiber surfaces. A single-enzymeapproach employed a conjugate between theNeocallimastix patriciarumCel6A cellulose-bindingmodule and lipase B fromCandida antarctica(CBM-CALB) to enhance theaccessibility of the enzyme to the target hydroxyl groups. READ MORE

4. 2. Tolerance and injury mechanisms in the developing CNS

   Author : Malin Gustavsson; Göteborgs universitet; []
   Keywords : hypoxia-ischemia; neonatal; brain; PARP-1; tolerance; global gene expression; apoptosis; cerebral blood flow;

   Abstract : The pathophysiological mechanisms underlying the development of hypoxic-ischemic (HI) brain injury has been the subject of extensive research yet a neuroprotective strategy to limit its progression is lacking.OBJECTIVES: The aim of the present thesis was to obtain a better understanding of the mechanisms involved in neonatal HI, specifically to study I) the involvement of Poly ADP-ribose) polymerase (PARP)-1 in HI, II) the effect of hypoxic PC on brain injury and function after HI in the long-term perspective, III) the effect of hypoxic PC on global gene expression, in particular the involvement of apoptosis related genes, and IV) the vascular response to hypoxic PC. READ MORE