Search for dissertations about: "Mammalian cell expression"

Showing result 1 - 5 of 254 swedish dissertations containing the words Mammalian cell expression.

  2. 1. Regulation of site-selective A-to-I RNA editing : During mammalian brain development

    Author : Helene Wahlstedt; Marie Öhman; Mary O'connell; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA editering; ADAR; brain development; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Abstract : Adenosine (A) to inosine (I) RNA editing is a widespread post-transcriptional mechanism in mammals that contributes to increase the protein diversity. Adenosine deaminases that act on RNA (ADARs) are the enzymes catalyzing RNA editing. ADARs are particularly active within the brain where they act on transcripts involved in neurotransmission. READ MORE

  4. 2. Estrogen receptor expression in relation to pain modulation and transmission : experimental studies in rats

    Author : Åsa Amandusson; Anders Blomqvist; Kaj Fried; Ola Hermanson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical cell biology; Medicinsk cellbiologi; Medical Cell Biology; Medicinsk cellbiologi; MEDICINE;

    Abstract : Estrogens have a remarkably wide range of actions in the mammalian brain. They not only play a pivotal role in reproductive behavior and sexual differentiation, but also contribute to e.g. thermoregulation, feeding, memory, neuronal survival and the perception of somatosensory stimuli. READ MORE

  5. 3. Expression and Regulation of Neuropeptide Y (NPY) in the Islets of Langerhans

    Author : Ulrika Myrsén Axcrona; Neuroendokrin cellbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; regulatory peptides; diabetes; glucocorticoids; beta cell; islet hormones; neuropeptide Y; insulin; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : This thesis deals with the expression, localization and regulation of neuropeptide Y (NPY) in the pancreatic islets of Langerhans under normal and experimental conditions. NPY is widely distributed in the mammalian nervous system and belongs to a family of closely related petides also comprising peptide YY (PYY) and pancreatic polypeptide (PP). READ MORE

  6. 4. Cell Behavior and the Role of Profilin

    Author : Yu Li; Roger Karlsson; Christophe Ampe; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Abstract : Profilin is a key regulator of the microfilament system. It binds to actin monomers in a 1:1 complex, forming the profilin:actin complex, which is the major precursor of actin for filament formation in vivo. The distribution of profilin has been studied in a variety of cells. It is present not only in the cytoplasm but also in the nucleus. READ MORE

  7. 5. Gene regulation by chromatin remodelling complexes : SWI/SNF complex in mRNA processing and B-WICH complex in ribosomal gene expression

    Author : Antoni Gañez Zapater; Ann-Kristin Östlund-Farrants; Christopher W.J. Smith; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chromatin remodelling; SWI SNF; Brg1; Brm; alternative splicing; cleavage and polyadenylation; B-WICH; WSTF; ribosomal genes; Cell Biology; cellbiologi;

    Abstract : The aim of this project is to investigate the roles of chromatin remodelling complexes in gene regulation. It is focused on two groups of chromatin complexes: the mammalian BRG1 and BRM SWI/SNF complexes and the ISWI-containing B-WICH complex.Study 1 investigates the role of SWI/SNF complexes in alternative splicing. READ MORE