Search for dissertations about: "Matilda Thorén"

Found 1 swedish dissertation containing the words Matilda Thorén.

2. 1. Hypoxic Adaptation and Arsenic Trioxide Treatment in Small Cell Lung Carcinoma

   Author : Matilda Thorén; Institutionen för translationell medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small cell lung carcinoma; arsenic trioxide; hypoxia; hypoxia-inducible factors; survival; proliferation; glycolysis; glutamine metabolism; MYC;

   Abstract : Small cell lung carcinoma (SCLC) is a very aggressive solid tumor and is often widely metastasized by the time of diagnosis. Despite good response to the initial chemotherapy, SCLC cells often develop multidrug resistance to conventionally used chemotherapeutic drugs, which cause almost all SCLC tumors to relapse. READ MORE