Search for dissertations about: "Mazin Magzoub"

Found 1 swedish dissertation containing the words Mazin Magzoub.

2. 1. Cell-penetrating peptides in model membrane systems : Interaction, structure induction and membrane effects

   Author : Mazin Magzoub; Astrid Gräslund; Steven Dowdy; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; Molekylär biofysik;

   Abstract : Despite continuing advances in the development of macromolecules, including peptides, proteins, and oligonucleotides, for therapeutic purposes, the successful application of these hydrophilic molecules has so far been hampered by their inability to efficiently traverse the plasma membrane. The discovery of a class of peptides (cell-penetrating peptides, CPPs) with the ability to mediate the non-invasive and efficient import of a whole host of cargoes, both in vitro and in vivo, has provided a new means by which the problem associated with cellular delivery can be circumvented. READ MORE