Search for dissertations about: "Medical Chemistry"
Showing result 1 - 5 of 536 swedish dissertations containing the words Medical Chemistry.
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1. Extracellular Matrix Based Materials for Tissue Engineering
Abstract : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. READ MORE
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2. Biomolecule Trapping With Stimuli-Responsive Polymer Coated Nanostructures
Abstract : Trapping biomolecules in nanosized gaps is of great interest in novel systems for single molecule analysis and membranes, which filter biomolecules. Current platforms are lacking in full functionality to facilitate biomolecule trapping and transport in their native environment and without covalent tethering to surfaces. READ MORE
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3. On the Versatility of Microwave-Assisted Chemistry : Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry
Abstract : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. READ MORE
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4. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence
Abstract : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. READ MORE
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5. Development of advanced chemical biology tools for microbiome metabolism : Chemoselective probes for enhanced metabolomics analysis
Abstract : The human microbiome has a profound impact on host physiology by generating highly reactive compounds that can contribute to the development of diseases. These microbial metabolites have a substantial potential that can serve as valuable indicators or biomarkers for different health conditions. READ MORE