Search for dissertations about: "Medicinska vetenskapsområdet"

Found 3 swedish dissertations containing the words Medicinska vetenskapsområdet.

  1. 1. Predictors of Dementia : Insulin, Fatty Acids and Vascular Risk Factors

    Author : Elina Rönnemaa; Lena Kilander; Lars Lannfelt; Björn Zethelius; Laura Fratiglioni; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dementia; Alzheimer’s disease; vascular dementia; insulin secretion; diabetes; fatty acids; epidemiology; vascular risk factors; Geriatrics; Geriatrik;

    Abstract : Identification of modifiable risk factors for Alzheimer’s disease (AD) is crucial in order to diminish suffering from this devastating disease. The aim of this thesis was to investigate if different aspects of glucose metabolism, insulin, fatty-acid composition or other vascular risk factors predict the future development of AD and dementia. READ MORE

  2. 2. The Neurological Wake-up Test in Neurocritical Care

    Author : Karin Skoglund; Niklas Marklund; Per Enblad; Tiit Mathiesen; Uppsala universitet; []
    Keywords : Intracranial pressure; Cerebral perfusion pressure; Propofol sedation; Wake-up test; stress hormones; intracerebral microdialysis; brain tissue oxygenation; jugular venous oxygenation; Neurokirurgi; Neurosurgery;

    Abstract : The neurological wake-up test, NWT, is a clinical monitoring tool that can be used to evaluate the level of consciousness in patients with traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH) during neurocritical care (NCC). Since patients with severe TBI or SAH are often treated with mechanical ventilation and sedation, the NWT requires that the continuous sedation is interrupted. READ MORE

  3. 3. Cyclotides : Tuning Parameters Toward Their Use in Drug Design

    Author : Mariamawit Yonathan Yeshak; Ulf Göransson; Lars Bohlin; Kaleab Asres; Robert Kiss; Uppsala universitet; []
    Keywords : cyclotide; Viola abyssinica; Viola odorata; Extraction; Violaceae; vaby; cytotoxic; genotoxic; cell penetrating; microautoradiography; LC-MS; comet assay; cycloviolacin O2; Farmakognosi; Pharmacognosy;

    Abstract : Cyclotides are plant proteins with a unique topology, defined as the cyclic cystine knot motif. The motif endows cyclotides with exceptional chemical and biological stability. They also exhibit a wide range of biological activities including insecticidal, cytotoxic, anti-HIV and antimicrobial effects. READ MORE