Search for dissertations about: "Membrane model"

Showing result 1 - 5 of 464 swedish dissertations containing the words Membrane model.

  1. 1. Exploring the Interplay of Lipids and Membrane Proteins

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Candan Ariöz; Stockholms universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; biokemi; Biochemistry;

    Abstract : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. READ MORE

  2. 2. The Membrane Proteome Evolution, Characteristics and Classification

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Markus Sällman Almén; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Membrane proteome; molecular evolution; GPCRs; Dispanins; IFITM; Medicinsk vetenskap; Medical Science;

    Abstract : Membrane proteins are found in all kingdoms of life and are essential for cellular interactions with the environment. Although a large research effort have been put into this group many membrane proteins remains uncharacterized, both in terms of function and evolutionary history. READ MORE

  3. 3. Cell-penetrating peptides in model membrane systems : Interaction, structure induction and membrane effects

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Mazin Magzoub; Stockholms universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Molecular biophysics; NATURVETENSKAP Kemi Molekylär biofysik;

    Abstract : Despite continuing advances in the development of macromolecules, including peptides, proteins, and oligonucleotides, for therapeutic purposes, the successful application of these hydrophilic molecules has so far been hampered by their inability to efficiently traverse the plasma membrane. The discovery of a class of peptides (cell-penetrating peptides, CPPs) with the ability to mediate the non-invasive and efficient import of a whole host of cargoes, both in vitro and in vivo, has provided a new means by which the problem associated with cellular delivery can be circumvented. READ MORE

  4. 4. Polarized light spectroscopy studies of model membranes and DNA

    University dissertation from Chalmers University of Technology

    Author : Maxim Kogan; Chalmers tekniska högskola.; Chalmers University of Technology.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bimolecular probe; DNA; emission; linear dichroism; lipid bilayer; membrane orientation; membrane model; ruthenium dipyridophenazine complex;

    Abstract : Over the past decades Linear Dichroism (LD) spectroscopy has proven to be a powerful tool for studies of structure and functioning of different cell constituents, including DNA, cell membranes and proteins. Due to structural complexity of cell constituents, the LD studies of biomolecules depend on development of simplified model systems, which can mimic the original structure and functionality of the cell components. READ MORE

  5. 5. DNA-Controlled Lipid-Membrane Fusion

    University dissertation from Chalmers University of Technology

    Author : Lisa Simonsson; Chalmers tekniska högskola.; Chalmers University of Technology.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biofysik; Biophysics; biomembranes; membrane fusion; vesicles; lipid bilayer; self-assembly; DNA; site-specificity; diffusion; model system; exocytosis; total internal reflection fluorescence microscopy; TIRF microscopy; fluorescence resonance energy transfer; FRET;

    Abstract : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. We have demonstrated that short DNA oligonucleotides, membrane-attached via CH in an orientation that mimics the overall zipperlike architecture of fusion-inducing proteins, induce fusion of both suspended vesicles and vesicles site-specifically tethered to SLBs. READ MORE